Results 241 to 250 of about 34,438,554 (301)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Polish adaptation and validation of the sustainable career scale. [PDF]

PLoS One
Grobelny J, Russo A, Klakus M, Zammitti A.   +3 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Development of Design-Phase Digital Twin for Structural Optimization of a Biomedical Device. [PDF]

Int J Numer Method Biomed Eng
Pinol TR, Prentice LH, Fox K, Pang TY.
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Associations Between Childhood Trauma and Personality Functioning and Maladaptive Personality Trait Domains in South Korea: An Alternative DSM-5 Model Approach. [PDF]

Personal Ment Health
Lee K, Jo S, Kim B, Ahn H.
europepmc   +1 more source

Global monitoring of methane point sources using deep learning on hyperspectral radiance measurements from EMIT. [PDF]

Proc Natl Acad Sci U S A
Batchu VV, Conserva M, Wilson A, Michalak AM, Gulshan V, Brodrick PG, Thorpe AK, Arsdale CV.   +7 more
europepmc   +1 more source

Machine learning combining FIT with up to 1,025 clinical variables: limited referral reduction but potential for faster diagnosis

Tamm A, Shine B, James T, Withers J, Salih H, East JE, Oke J, Davies J, Morris E, Nicholson BD.   +9 more
europepmc   +1 more source

Time to Cancer Screening Completion Following an SMS Reminder Intervention in a Large Federally Qualified Health Center Network: Secondary Data Analysis. [PDF]

JMIR Mhealth Uhealth
Xu T, Chavez S, King B, Ramirez-Pulido G, Ojinnaka CO, Osayi D, Kounga V, Adepoju OE.   +7 more
europepmc   +1 more source