Results 101 to 110 of about 35,199,249 (362)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Model Aktivitas Praktikum Lapangan Berbasis Ergonomi (Apelerg) Memperbaiki Respon Fisiologis Tubuh, Menurunkan Kelelahan, dan Meningkatkan Kinerja, Dibandingkan dengan Model Lama (Apel), pada Mahasiswa Fmipa Unima [PDF]

open access: yes, 2009
Aktivitas praktikum lapangan merupakan kegiatan yang dilakukan sebagaiimplementasi kurikulum akademik di Jurusan Fisika FMIPA UNIMA. Sebagaiimplementasi kurikulum tersebut telah dibuat model aktivitas praktikum lapangan (modelAPeL) dan telah digunakan ...
Adiputra, N. (Nyoman)   +3 more
core  

A Note on Model Complete Models and Generic Models [PDF]

open access: yesProceedings of the American Mathematical Society, 1972
We prove that there are many maximum model complete (= generic) models, and that there exists an (uncountable) theory with no generic models.
openaire   +3 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

MODEL AND MODELING

open access: yes, 2023
This article gives an idea about the object and model, their similarities, modeling and types of models.
openaire   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Coupling of mitochondrial function and skeletal muscle fiber type by a miR‐499/Fnip1/AMPK circuit

open access: yesEMBO Molecular Medicine, 2016
Upon adaption of skeletal muscle to physiological and pathophysiological stimuli, muscle fiber type and mitochondrial function are coordinately regulated.
Jing Liu   +13 more
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Cooperatives a model to improve organic seed production (Liveseed Practice Abstract) [PDF]

open access: yes, 2019
Building cooperatives sounds easier than it is. Some general recommendations are: - Build trust – an on-going process - Define clear goals – common aims, clear rules - Have a clear timeline – go step by step - Communicate clearly – among members ...
Nuijten, Edwin
core  

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