Results 161 to 170 of about 58,575,561 (400)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Model of Formin-Associated Actin Filament Elongation [PDF]
Dimitrios Vavylonis +3 more
openalex +1 more source
Informative Features for Model Comparison [PDF]
Given two candidate models, and a set of target observations, we address the problem of measuring the relative goodness of fit of the two models. We propose two new statistical tests which are nonparametric, computationally efficient (runtime complexity ...
Gretton, Arthur +5 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Small-Signal Dynamic DQ Model of Modular Multilevel Converter for System Studies [PDF]
Ali Far, Dragan Jovcic
openalex +1 more source
Artificial intelligence (AI)‐driven strategic business model innovations in small‐ and medium‐sized enterprises. Insights on technological and strategic enablers for carbon neutral businesses [PDF]
Aqueeb Sohail Shaik +4 more
openalex +1 more source
The attached document provides an introduction to the FairShares Model, a new brand and concept for self-governing social enterprises operating under Company and Co operative ...
Dickins, Nicci +2 more
core
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

