Results 231 to 240 of about 58,575,561 (400)

Modelling the role of task in the control of gaze

, 2009
Dana H. Ballard, Mary Hayhoe
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Albumin Levels Are Predictive of Cachexia-Induced Time-Dependent Clearance of Therapeutic Antibodies: A Physiologically Based Pharmacokinetic Model of Durvalumab. [PDF]

CPT Pharmacometrics Syst Pharmacol
Proctor JR, Wong H.
europepmc   +1 more source

Development of Fully Coupled Aeroelastic and Hydrodynamic Models for Offshore Wind Turbines

, 2006
Jason Jonkman, Paul D. Sclavounos
openalex   +2 more sources

Using machine learning approach for microseismic events recognition in underground excavations: Comparison of ten frequently-used models

, 2020
Yuanyuan Pu, Derek B. Apel, Robert A. Hall   +2 more
openalex   +2 more sources

A Novel Entropy-Fuzzy PIPRECIA-DEA Model for Safety Evaluation of Railway Traffic [PDF]

, 2020
Aleksandar Blagojević, Željko Stević, Dragan Marinković, Sandra Kasalica, Snježana Rajilić   +4 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Validating Physiologically-Based Pharmacokinetic Models Using the Continuous Ranked Probability Score: Beyond Being Correct on Average. [PDF]

CPT Pharmacometrics Syst Pharmacol
Sluijterman L, van Borselen M, Greupink R, IntHout J.   +3 more
europepmc   +1 more source

Learning from video modeling examples: Content kept equal, adults are more effective models than peers

, 2016
Vincent Hoogerheide, Margot van Wermeskerken, Sofie M. M. Loyens, Tamara van Gog   +3 more
openalex   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source