Results 271 to 280 of about 58,575,561 (400)

Managing Drug-Drug Interactions Involving the Non-Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling. [PDF]

CPT Pharmacometrics Syst Pharmacol
Zhou Z, Ainslie GR, Li M, Dinh J, Zamek-Gliszczynski MJ, Zhao P, Paine MF.   +6 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling truncated and censored data with the diffusion model in Stan. [PDF]

Behav Res Methods
Henrich F, Klauer KC.
europepmc   +1 more source

Antitumor effects of regorafenib and sorafenib in preclinical models of hepatocellular carcinoma [PDF]

, 2017
Maria Kissel, Sandra Berndt, Lukas Fiebig, Simon Kling, Qunsheng Ji, Qingyang Gu, Tina Lang, Frank‐Thorsten Hafner, Michael Teufel, Dieter Zopf   +9 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome

, 2018
Camilla Teng, Man-Chun Ting, D’Juan T. Farmer, Mia Brockop, Robert E. Maxson, J. Gage Crump   +5 more
openalex   +1 more source

Comparative infection modeling and control of COVID-19 transmission patterns in China, South Korea, Italy and Iran

, 2020
Junyu He, Guangwei Chen, Yutong Jiang, Runjie Jin, Ashton Shortridge, Susana Agustı́, Mingjun He, Jiaping Wu, Carlos M. Duarte, George Christakos   +9 more
openalex   +2 more sources

The Internationalization Process of the Firm—A Model of Knowledge Development and Increasing Foreign Market Commitments

, 1977
J. Johanson, J. Vahlne
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Intelligent diagnosis method for river and lake ecosystem health based on improved slime mold algorithm-optimized SVR. [PDF]

PLoS One
Chi R, Da Y, Li W, Wen D.
europepmc   +1 more source