Results 71 to 80 of about 35,199,249 (362)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

The impact of time‐varying sea surface temperature on UK regional atmosphere forecasts

open access: yesMeteorological Applications, 2021
A new approach to improve the ocean surface boundary condition used in regional numerical weather prediction is proposed. Typically, regional atmosphere forecast systems assume a fixed sea surface temperature during a simulation.
Sana Mahmood   +5 more
doaj   +1 more source

Is the Voter Model a Model for Voters? [PDF]

open access: yesPhysical Review Letters, 2014
The voter model has been studied extensively as a paradigmatic opinion dynamics' model. However, its ability for modeling real opinion dynamics has not been addressed. We introduce a noisy voter model (accounting for social influence) with agents' recurrent mobility (as a proxy for social context), where the spatial and population diversity are taken ...
Fernández-Gracia, Juan   +4 more
openaire   +4 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Model-independent measurements of the sodium magneto-optical trap's excited-state population [PDF]

open access: yes, 2018
We present model-independent measurements of the excited-state population of atoms in a sodium (Na) magneto-optical trap (MOT) using a hybrid ion-neutral trap composed of a MOT and a linear Paul trap (LPT).
Entner, S. A.   +5 more
core   +2 more sources

Generation and characterization of a tamoxifen-inducible lineage tracing tool Cd2-P2A-CreERT2 knock-in mice

open access: yesFrontiers in Immunology
IntroductionThe new targeted gene editing technologies, such as the CRISPR/Cas system, enable researchers to insert or delete genes at targeted loci efficiently.
Yang Guo   +7 more
doaj   +1 more source

“It is like an umbrella covering you, yet it does not protect you from the rain”: a mixed methods study of insurance affordability, coverage, and financial protection in rural western Kenya

open access: yesInternational Journal for Equity in Health, 2023
Countries in Sub-Saharan Africa are increasingly adopting mandatory social health insurance programs. In Kenya, mandatory social health insurance is being implemented through the national health insurer, the National Hospital Insurance Fund (NHIF), but ...
Beryl Maritim   +9 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy