Results 71 to 80 of about 8,262,723 (268)

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Protein Structure Modeling with MODELLER

, 2014
Genome sequencing projects have resulted in a rapid increase in the number of known protein sequences. In contrast, only about one-hundredth of these sequences have been characterized at atomic resolution using experimental structure determination methods.
Webb, Benjamin, Sali, Andrej
openaire   +6 more sources

The Modeling Process for Stage Models

Journal of Organizational Computing and Electronic Commerce, 2010
This is the authors' final and acceptet version of the article, post refereeing.
Hans Solli-Sæther, Petter Gottschalk
openaire   +2 more sources

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration

Journal of Neuroinflammation, 2019
Background Metabolic dysfunction and neuroinflammation are increasingly implicated in Parkinson’s disease (PD). The pentose phosphate pathway (PPP, a metabolic pathway parallel to glycolysis) converts glucose-6-phosphate into pentoses and generates ...
Dezhen Tu, Yun Gao, Ru Yang, Tian Guan, Jau-Shyong Hong, Hui-Ming Gao   +5 more
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Implementation determinants of risk-stratified gestational diabetes mellitus screening in community-based women’s peer groups in rural western Kenya

BMC Pregnancy and Childbirth
Background Gestational Diabetes Mellitus (GDM) contributes to maternal and neonatal complications and is a growing concern in Kenya. The 2-hour oral glucose tolerance test (OGTT) is recommended to diagnose GDM between 24 and 28 weeks of pregnancy, but ...
Rachel Ogumbo, Violet Naanyu, Laura Ruhl, James Akiruga, Evelyn Kaluhi, Sheilah Chelagat, Hector Nyaboga, Sonak Pastakia   +7 more
doaj   +1 more source

Generation and characterization of a tamoxifen-inducible lineage tracing tool Cd2-P2A-CreERT2 knock-in mice

Frontiers in Immunology
IntroductionThe new targeted gene editing technologies, such as the CRISPR/Cas system, enable researchers to insert or delete genes at targeted loci efficiently.
Yang Guo, Mengyan Zhu, Zhilan Yu, Qing Li, Yanjuan Chen, Lei Ci, Ruilin Sun, Ruling Shen   +7 more
doaj   +1 more source

Sensitivity of the 2018 UK summer heatwave to local sea temperatures and soil moisture

Atmospheric Science Letters, 2020
The impact of local climate conditions on air temperatures during a hot summer period over the United Kingdom in 2018 is studied using simple sensitivity experiments with a state‐of‐the‐art regional numerical weather prediction system.
Jon C. Petch, Chris J. Short, Martin J. Best, Mark McCarthy, Huw W. Lewis, Simon B. Vosper, Mark Weeks   +6 more
doaj   +1 more source

A Note on Model Complete Models and Generic Models [PDF]

Proceedings of the American Mathematical Society, 1972
We prove that there are many maximum model complete (= generic) models, and that there exists an (uncountable) theory with no generic models.
openaire   +2 more sources