Results 201 to 210 of about 466,753 (264)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

AdaFed-LDR: Adaptive Federated Learning with Layerwise Dynamics Regularization for Robust Wi-Fi Localization. [PDF]

Sensors (Basel)
Harada K, Natori H, Koike M, Mineno H.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Trust-Aware and Energy-Efficient Federated Learning for Secure Sensor Networks at the Edge. [PDF]

Sensors (Basel)
Reis MJCS.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

FedDriftGuard adaptive federated learning with differential privacy for concept drift in edge environments. [PDF]

Sci Rep
Sudhakar K, Jayasree A, Sundaragiri D, Talluri U, Bhusarapu HN, Sreenivas TS.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

EcoStack-Pro: an adaptive federated learning framework for interpretable ESG auditing across heterogeneous industrial sectors. [PDF]

Front Artif Intell
Azad MAK, Masum AKM, Rahman MA, Bhuiyan MTA, Noori FM, Uddin MZ.   +5 more
europepmc   +1 more source

Automatic Localization of Stable Highest Dominant Frequency Area in AF Patients Based on Spatial Aggregation. [PDF]

Bioengineering (Basel)
Huang T, Jiang Y, Wu X.
europepmc   +1 more source

Fragmentation and aggregation of cyanobacterial colonies. [PDF]

Elife
Sinzato YZ, Uittenbogaard R, Visser PM, Huisman J, Jalaal M.   +4 more
europepmc   +1 more source