Results 121 to 130 of about 660,853 (292)

Fishing ship trajectory prediction considering trajectory behavior characteristics

Journal of Ocean Engineering and Science
Understanding and accurately predicting the trajectory changes of fishing ships is of great significance for effectively preventing collisions between merchant and fishing ships and enhancing the safety supervision of fishing ships.
Jianwen Ma, Zhaojun Chen, Jingru Yuan, Jinyu Li, Guoxin Liu   +4 more
doaj   +1 more source

iGrace – Emotional Computational Model for EmI Companion Robot.

, 2009
We will discuss in this chapter the research in the field of emotional interaction, to maintain a non-verbal interaction with children from 4 to 8 years. This work fits into the EmotiRob project, whose goal is to comfort the children vulnerable and / or in hospitalization with an emotional robot companion.
Saint-Aimé, Sébastien, Le Pévédic, Brigitte, Duhaut, Dominique   +2 more
openaire   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Recommendations for designing conversational companion robots with older adults through foundation models

Frontiers in Robotics and AI
Companion robots are aimed to mitigate loneliness and social isolation among older adults by providing social and emotional support in their everyday lives.
Bahar Irfan, Sanna Kuoppamäki, Gabriel Skantze   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Binary Origin for Ultralong-period Radio Pulsars

The Astrophysical Journal Letters
We propose a possible binary evolution model for the formation of ultralong-period pulsars. The model involves two key stages: first, a neutron star (NS) in wide binaries undergoes an effective spin-down phase through wind-fed accretion from its massive ...
Ying-Han Mao, Xiang-Dong Li, Dong Lai, Zhu-Ling Deng, Hao-Ran Yang   +4 more
doaj   +1 more source

Interferometric view into RT Pav’s long secondary period

Astronomy & Astrophysics
Context. Long secondary periods (LSPs) occur in roughly one third of evolved stars, yet their origin remains uncertain. Two leading hypotheses are oscillatory convective modes and a binary companion enshrouded in dust. Aims. We investigate the LSP in the
Courtney-Barrer B., Haubois X., Wood P., Dionese D., Decin L., Paladini C., El Mellah I., Defrère D., Ireland M.   +8 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source