Results 41 to 50 of about 98,477 (264)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Le rôle des forêts et des arbres dans l'adaptation sociale à la variabilité et au changement climatiques [PDF]

open access: yes, 2012
Les écosystèmes fournissent d'importants services qui peuvent aider les populations à s'adapter à la variabilité et au changement climatiques. Reconnaissant ce rôle des écosystèmes, plusieurs organisations internationales et non gouvernementales ont ...
Djoudi, Houria   +3 more
core   +2 more sources

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Partage des connaissances et résilience organisationnelle : le cas de la numérisation de l'armée de terre [PDF]

open access: yes, 2008
International audienceThis communication displays the case of a new information technology implementation in a specific organization. This new IT has implied problems in terms of knowledge sharing.
Lancini, Agnes, Lebraty, Jean-Fabrice
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Psychometric properties of the Spanish version of the Protective Factors of Resilience Scale (PFRS)

open access: yesAnales de Psicologia
: Background: Resilience is de capacity to recover from difficulties; most people can recover optimally from and adapt to stressful life events through the effect of protective factors.
Eva León   +2 more
doaj   +1 more source

A Coupled CA Urban Development Model (UDM) and Urban Fabric Generator (UFG) for the Assessment of Climate Hazards on Future Urban Development [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Cellular Automata (CA) spatial models have become a de facto means by which to simulate future scenarios of land use activity, particularly urban development.
S. Barr   +5 more
doaj   +1 more source

Lutter contre les insectes nuisibles en agriculture biologique : intervenir en harmonie face à la complexité [PDF]

open access: yes, 2006
Les systèmes agricoles en gestion biologique se caractérisent par une grande biodiversité et une forte complexité. La biodiversité est associée à une faune entomophage variée et abondante qui permet une meilleure lutte naturelle contre les insectes ...
Boisclair, Josée, Estevez, Bernard
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Gestion participative, capabilités et résilience dans les forêts classées de Côte d’Ivoire [PDF]

open access: yes, 2013
Dans le domaine de la gestion durable des ressources naturelles, l’approche participative est apparue depuis une vingtaine d’années comme une voie alternative de gestion entre l’Etat et le marché.
Koffi, Kouamékan J.M.
core  

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