Results 41 to 50 of about 91,698 (215)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

LA RESILIENCIA: UNA MIRADA DESDE LA ENFERMERÍA RESILIENCE: A VIEW FROM NURSING

Ciencia y Enfermería, 2010
El objetivo del artículo es demostrar la importancia del concepto de resiliencia para los profesionales de enfermería, presentando una refexión teórica acerca de las distintas definiciones del concepto y dando a conocer además una aproximación de un ...
Juana Elena Cortés Recaball
doaj  

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Exploration of Dual-Carbon Target Pathways Based on Machine Learning Stacking Model and Policy Simulation—A Case Study in Northeast China

Land
Northeast China, a traditional heavy industrial base, faces significant carbon emissions challenges. This study analyzes the drivers of carbon emissions in 35 cities from 2000–2022, utilizing a machine-learning approach based on a stacking model.
Xuezhi Ren, Jianya Zhao, Shu Wang, Chunpeng Zhang, Hongzhen Zhang, Nan Wei   +5 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Enfoque sistémico para el diseño de sistemas energéticos acuícolas resilientes: discusión aplicada al caso de una empresa de cultivos Systematic approach to design resilient energy systems to aquaculture: discussion applied in a private hatchery

Latin American Journal of Aquatic Research, 2012
El presente trabajo documenta experiencias en la aplicación del enfoque sistémico a un proceso productivo en el campo de la acuicultura. Particularmente, se analiza el modelo de producción de energía, orientado a la resiliencia y baja emisión de carbono,
Marcelo Concha, Claudia Cerda, Mariana Zappi   +2 more
doaj  

Understanding Resilience Factors Among Caregivers of People with Alzheimer’s Disease in Spain

Psychology Research and Behavior Management, 2020
Noelia Durán-Gómez,1 Jorge Guerrero-Martín,1 Demetrio Pérez-Civantos,2 Casimiro Fermín López Jurado,1 Patricia Palomo-López,1 Macarena C Cáceres1 1Department of Nursing, University of Extremadura ...
Durán-Gómez N, Guerrero-Martín J, Pérez-Civantos D, López Jurado CF, Palomo-López P, Cáceres MC   +5 more
doaj  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Risk and resilience in eating disorders: differentiating pathways among psychosocial predictors

Journal of Eating Disorders
Objective Eating disorders (EDs) represent a rising global health concern. The current study takes a multivariate approach to examine psychological (i.e., perfectionism, anxiety sensitivity [AS], emotion dysregulation) and sociocultural factors (i.e ...
Maria Bazo Perez, Leslie D. Frazier
doaj   +1 more source

Treating the Symptoms as Well as the Root Causes: How the Digital Economy Can Mitigate the Negative Impacts of Land Resource Mismatches on Urban Ecological Resilience

Land
In the era of the digital economy (DE), the traditional economic growth paradigm is no longer applicable. To explore whether the DE can improve the urban ecological problems left behind by rough economic growth, this study examines the effects of land ...
Huangying Gu, Guanyu Guo, Chengming Li
doaj   +1 more source