Results 41 to 50 of about 235,774 (263)

Model-Driven Evolution of Software Architectures

11th European Conference on Software Maintenance and Reengineering (CSMR'07), 2007
This paper gives an overview of a Ph.D.-project that investigates approaches to support the evolution of software architectures. Particularly, we focus on the use of model-driven techniques in the context of software product-lines. We recognize four tasks related to software evolution: evaluation, conformance checking, migration, and documentation.
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A Model Driven Framework for Collaborative and Dynamic Design and Implementation of NoSQL-Oriented Data warehouses

Jordanian Journal of Computers and Information Technology
Nowadays, modernizing the data warehouse ecosystem is a key challenge in decision support systems. This modernization is crucial for ensuring scalability and meeting evolving business requirements, especially with the advent of big data.
Khadija Letrache, Mohammed Ramdani
doaj   +1 more source

Survey on Cloud Robotics Architecture and Model-Driven Reference Architecture for Decentralized Multicloud Heterogeneous-Robotics Platform

IEEE Access, 2021
Robotics engineering is gradually becoming an essential part of our daily life. However, it has been generating Big Data and seeking large computation cost because of the diversified sensors and processing requirements involved in heterogeneous robotics ...
Akila Siriweera, Keitaro Naruse
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Comparing Transformation Possibilities of Topological Functioning Model and BPMN in the Context of Model Driven Architecture

Applied Computer Systems, 2016
The approach called “Topological Functioning Model for Software Engineering” (TFM4SE) applies the Topological Functioning Model (TFM) for modelling the business system in the context of Model Driven Architecture.
Solomencevs Artūrs
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A model transformation framework to increase OCL usability

Journal of King Saud University: Computer and Information Sciences, 2016
The usability of a modeling language has a direct relationship with several factors of models constructed with the modeling language, such as time required and accuracy.
Samin Salemi, Ali Selamat, Marek Penhaker   +2 more
doaj   +1 more source