Results 61 to 70 of about 2,375,285 (268)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Promoting tissue repair with plant-derived compounds: evidence and mechanisms from zebrafish studies

Frontiers in Nutrition
The pursuit of strategies to enhance tissue repair is a central challenge in regenerative medicine, where plant-derived compounds offer immense therapeutic potential due to their multi-target, systems-level activities.
Xiang Meng, Xiang Meng, Xiang Meng, Xuting Song, Xuting Song, Xuting Song, Lixia Zhu, Lixia Zhu, Lixia Zhu, Yiming Wang, Yiming Wang, Yiming Wang, Xianghe Meng, Xianghe Meng, Yufang Tang, Yufang Tang, Kobil A. Bobokalonov, Min He, Min He, Min He, Mengmeng Sun, Mengmeng Sun, Mengmeng Sun, Meiying Jin, Meiying Jin   +24 more
doaj   +1 more source

Agent‐Based Modeling of Alternative Futures in the British Land Use System

Earth's Future, 2022
Socio‐economic scenarios such as the Shared Socioeconomic Pathways (SSPs) have been widely used to analyze global change impacts, but representing their diversity is a challenge for the analytical tools applied to them. Taking Great Britain as an example,
C. Brown, B. Seo, P Alexander, V. Burton, E. A. Chacón‐Montalván, R. Dunford, M. Merkle, P. A. Harrison, R. Prestele, E. L. Robinson, M. Rounsevell   +10 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Comparing Model Representations of Physiological Limits on Transpiration at a Semi‐Arid Ponderosa Pine Site

Journal of Advances in Modeling Earth Systems, 2022
Mechanistic representations of biogeochemical processes in ecosystem models are rapidly advancing, requiring advancements in model evaluation approaches.
Linnia R. Hawkins, Maoya Bassouni, William R. L. Anderegg, Martin D. Venturas, Stephen P. Good, Hyojung J. Kwon, Chad V. Hanson, Richard P. Fiorella, Gabriel J. Bowen, Christopher J. Still   +9 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Simple Models Outperform More Complex Big‐Leaf Models of Daily Transpiration in Forested Biomes

Geophysical Research Letters, 2022
Transpiration makes up the bulk of total evaporation in forested environments yet remains challenging to predict at landscape‐to‐global scales. We harnessed independent estimates of daily transpiration derived from co‐located sap flow and eddy‐covariance
Ryan M. Bright, Diego G. Miralles, Rafael Poyatos, Stephanie Eisner   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis

Frontiers in Pharmacology
IntroductionThis study aims to investigate the progressive impact of chronic iron overload on the olfactory bulb, a region significantly affected in early neurodegenerative diseases like Parkinson’s and Alzheimer’s. The focus is on understanding how iron
Lin Deng, Lin Deng, Lin Deng, Qihui Luo, Qihui Luo, Yucong Liu, Yucong Liu, Yao Wang, Yao Wang, Zongliang Xiong, Zongliang Xiong, Hongping Wang, Lu Zhao, Lanlan Jia, Lanlan Jia, Riyi Shi, Chao Huang, Chao Huang, Zhengli Chen, Zhengli Chen   +19 more
doaj   +1 more source