Results 61 to 70 of about 20,676,866 (305)
The search for novel therapeutics for prevalent liver diseases such as metabolic dysfunction-associated steatotic liver disease, alcohol-related liver disease, and drug-induced liver injury is constrained by the methodological gaps in conventional ...
Yuliang Liu +14 more
doaj +1 more source
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Evaluating health risk models [PDF]
AbstractInterest in targeted disease prevention has stimulated development of models that assign risks to individuals, using their personal covariates. We need to evaluate these models and quantify the gains achieved by expanding a model to include additional covariates.
openaire +3 more sources
Evaluation of Markov Models with Discontinuities [PDF]
Background. Several methods, such as the half-cycle correction and the life-table method, were developed to attenuate the error introduced in Markov models by the discretization of time. Elbasha and Chhatwal have proposed alternative “corrections” based on numerical integration techniques.
Jorge Pérez-Martín +2 more
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Cardiovascular diseases (CVDs) are a major global health challenge, significantly impacting public health and healthcare systems. Ethnopharmacological remedies and botanical medicines are widely used for the prevention and treatment of CVDs due to their ...
Yiming Wang +23 more
doaj +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
A model for clinical evaluation
After grappling for years with the problems associated with clinical evaluation In nursing, and becoming increasingly am re of the importance of this aspect of the clinical teaching process, the researcher resolved to make an indepth study of the state of clinical evaluation in nursing. The study was undertaken in the second semester of1990.
openaire +4 more sources
Evaluation of the Snow Albedo Retrieved from the Snow Kernel Improved the Ross-Roujean BRDF Model
The original kernel-driven bidirectional reflectance distribution function (BRDF) models were developed based on soil-vegetation systems. To further improve the ability of the models to characterize the snow surface scattering properties, a snow kernel ...
Anxin Ding +10 more
doaj +1 more source
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Promoting tissue repair with plant-derived compounds: evidence and mechanisms from zebrafish studies
The pursuit of strategies to enhance tissue repair is a central challenge in regenerative medicine, where plant-derived compounds offer immense therapeutic potential due to their multi-target, systems-level activities.
Xiang Meng +24 more
doaj +1 more source

