Results 261 to 270 of about 58,163,280 (350)

Eravacycline and omadacycline Rescue multidrug-resistant Elizabethkingia anophelis: Triple-Model evaluation across in Vitro, Galleria mellonella, and murine bacteremia systems. [PDF]

J Adv Res
Hu S, Jiang L, Xu H, Meng X, Zhang D, Zhou D, Xiao Y, Zheng B.   +7 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Evaluation of the CGIAR Research Program on Livestock and Fish [PDF]

, 2016
CGIAR Independent Evaluation Arrangement
core  

Gas-Phase Water-Soluble Organic Carbon: CMAQ Model Evaluation in Baltimore County. [PDF]

ACS Earth Space Chem
Smith EN, Baker KR, El-Sayed MMH, Hennigan CJ, Rosanka S, Carlton AG.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Impact of agricultural industry transformation based on deep learning model evaluation and metaheuristic algorithms under dual carbon strategy. [PDF]

Sci Rep
Zhao X, Tang W, Liu Q, Cao H, Chen F.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Potential to perpetuate social biases in health care by Chinese large language models: a model evaluation study. [PDF]

Int J Equity Health
Liu C, Zheng J, Liu Y, Wang X, Zhang Y, Fu Q, Yu W, Yu T, Jiang W, Wang D, Liu C.   +10 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Image-Based Dietary Assessment Using the Swedish Plate Model: Evaluation of Deep Learning-Based You Only Look Once (YOLO) Models. [PDF]

JMIR Form Res
Chrintz-Gath G, Daivadanam M, Matta L, McKeever S.   +3 more
europepmc   +1 more source