Results 101 to 110 of about 20,606,201 (305)

Multiscale Applications of Two Online-Coupled Meteorology-Chemistry Models during Recent Field Campaigns in Australia, Part I: Model Description and WRF/Chem-ROMS Evaluation Using Surface and Satellite Data and Sensitivity to Spatial Grid Resolutions

open access: yesAtmosphere, 2019
Air pollution and associated human exposure are important research areas in Greater Sydney, Australia. Several field campaigns were conducted to characterize the pollution sources and their impacts on ambient air quality including the Sydney Particle ...
Yang Zhang   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

From Concept to Market: Ensemble Predictive Model for Research Project Crowdfunding Readiness

open access: yesSystems
This study introduces an ensemble model that integrates random forest, gradient boosting, and logistic regression to predict the success of crowdfunding campaigns.
Andreea Cristina Ionica   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An Evaluation of the World Bank Group’s Contributions

open access: yes, 2021
More than a decade has passed since the global economic and financial crisis rocked the world. A clear lesson that emerged from it was the importance of identifying and addressing country-specific vulnerabilities
Independent Evaluation Group
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Working together to strengthen skills : IDRC's strategic evaluation of capacity development, phase 3; developing the framework [PDF]

open access: yes, 2007
French version available in IDRC Digital Library: Renforcement concerté des capacités : phase 3 de l'évaluation stratégique des activités de renforcement des capacités du CRDI; élaboration du cadre d'évaluationThis “Evaluation Highlights” newsletter ...
IDRC. Evaluation Unit
core  

Formatting evaluation reports at IDRC

open access: yes, 2012
French version available in IDRC Digital Library: Présentation des rapports d'évaluation au CRDIThis one-pager provides a guideline to the structure and formatting of project summaries, evaluations and annexes for research partners, awardees, staff ...
IDRC. Evaluation Unit
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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