Results 51 to 60 of about 2,377,091 (269)

Sargassum pallidum reduces inflammation to exert antidepressant effect by regulating intestinal microbiome and ERK1/2/P38 signaling pathway

open access: yesFrontiers in Pharmacology
Immune inflammation is one of the main factors in the pathogenesis of depression. It is an effective and active way to find more safe and effective anti-inflammatory depressant drugs from plant drugs. The purpose of this study is to explore the potential
Dan Su   +10 more
doaj   +1 more source

Evaluation of Linear Kernel-Driven BRDF Models over Snow-Free Rugged Terrain

open access: yesRemote Sensing, 2023
Semi-empirical kernel-driven models have been widely used to characterize anisotropic reflectance due to their simple form and physically meaningful approximation.
Wenzhe Zhu   +5 more
doaj   +1 more source

A novel carcinogenic mouse model by site‐directed insertion of tandem human HRAS large DNA fragment into 15E1 site

open access: yesAnimal Models and Experimental Medicine
Background The precise insertion of large DNA fragments (>3–5 kb) remains one of the key obstacles in establishment of genetically modified murine models.
Susu Liu   +12 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

Applications and Extensions of Metric Stability Analysis

open access: yesPsych, 2023
Item response theory models and applications are affected by many sources of variability, including errors associated with item parameter estimation. Metric stability analysis (MSA) is one method to evaluate the effects of item parameter standard errors ...
Leah Feuerstahler
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

The Predictability of the Southern England 23 October 2022 Severe Downbursts

open access: yesAtmospheric Science Letters
Accurate prediction of damaging straight‐line wind events from convective storms relies heavily on storm morphology and nowcasting. Utilising the Microburst Wind Potential Index in ensemble forecasts we examine the predictability of its different ...
David L. A. Flack, Kenneth L. Pryor
doaj   +1 more source

Comparison of the Forecast Performance of WRF Using Noah and Noah-MP Land Surface Schemes in Central Asia Arid Region

open access: yesAtmosphere, 2022
The land surface scheme (LSS) plays a very important role in the forecast of surface meteorological elements in the Central Asia arid region. Therefore, two LSSs viz.
Chenxiang Ju   +7 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi   +10 more
wiley   +1 more source

New antidepressant mechanism of Yueju Pill: Increasing ghrelin level by inhibiting gastric mTOR/S6K signaling pathway and sensitizing hippocampal GHS-R

open access: yesHeliyon
Background and aim: Yueju Pill (YJ) not only has good antidepressant effect but also can effectively treat digestive system diseases. However,it remains unclear whether the mechanism of antidepressant action of YJ is related to the peripheral digestive ...
Zhentao Zhang   +8 more
doaj   +1 more source

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