Results 121 to 130 of about 2,401,837 (269)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Topic-Aware Summarization of Lived Health Care Experiences: Large Language Model Evaluation Study. [PDF]

JMIR Med Inform
Bilalpur M, Hamm ME, Lee YJ, Norman NG, Mctigue KM, Wang Y.   +5 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

In Vitro and In Ovo CAM Model Evaluation of Periosteum-Derived Micrografts. [PDF]

J Funct Biomater
Almujaydil R, McCann CJ, Nguyen L, D'Aiuto F.   +3 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Novel Potential Markers of Metabolic Dysfunction–Associated Steatohepatitis Prone to Hepatocellular Carcinoma

Canadian Journal of Gastroenterology and Hepatology
Chen Ling, Yuya Wang, Susu Liu, Guitao Huo, Yanwei Yang, Nan Xu, Hong Wang, Haoyang Zhao, Zeqiang Zhang, Rui Fu, Yuwei Zhao, Changfa Fan   +11 more
doaj   +1 more source

Vancomycin Therapeutic Drug Monitoring, Clinical Outcomes and Population Pharmacokinetic Model Evaluation in Neonates. [PDF]

Children (Basel)
Chung E, Tabbara N, Seto W, Shah V.
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Correction: Sargassum pallidum reduces inflammation to exert antidepressant effect by regulating intestinal microbiome and ERK1/2/P38 signaling pathway

Frontiers in Pharmacology
Dan Su, Qianmin Li, Xin Lai, Yonggui Song, Huizhen Li, Zhifu Ai, Qi Zhang, Wenxiang Shao, Ming Yang, Ming Yang, Genhua Zhu   +10 more
doaj   +1 more source

Expanding access to perinatal trauma care: A dual-model evaluation of perinatal narrative exposure therapy training. [PDF]

Psychol Trauma
Addante S, Miller ML, Meyer DJ, Stevens NR, Padin AC.   +4 more
europepmc   +1 more source