Results 121 to 130 of about 21,900,708 (303)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
A Method to Evaluate Response Models
, 2014 We are working towards computational models of mind of virtual characters that act as suspects in interview (interrogation) training of police officers. We implemented a model that calculates the responses of the virtual suspect based on theory and observation. We evaluated it by means of our test, the “Guess who you are talking to?‿ test. We show that
Bruijnes, Merijn +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Evaluation in brief: intervention orders and the intervention response model January 2015
, 2015 Intervention Orders and the Intervention Response Model: Evaluation Report 1 This report outlines the findings from a process evaluation of the first year of operation of Intervention Orders and the Intervention Response Model, conducted in 2012.
Office of Crime Statistics and Research (SA)
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Partial Evaluation in Meta Modeling [PDF]
, 2007 Meta modeling is a well-established technique to describe the structure modeling languages. Method engineering environments utilize the technique to provide a flexible environment for defining and adapting modeling environments. We show that basing meta modeling strictly on first-order logic provides not only clean semantics but also the ability to ...
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source