Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Collapsing Sparse Responses in Likert-Type Scale Data: Advantages and Disadvantages for Model Fit in CFA. [PDF]
Liu J, Bao Y, DiStefano C, Jiang W.
europepmc +1 more source
FIT Soul Fashion Show: 1983 part 2
The FIT Soul Club presents the 1983 Soul Fashion Show. Featuring work by student designers and alumni Roger Hinds, Jurvis Jarvis, Cheryl Williams, Keith Martin and Alexander Young as Young Martin, Ron Chew, Cheryl McKenzie, Sherri Hobson, Steve Cutting ...
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Simultaneous detection of gradual and abrupt structural changes in Bayesian longitudinal modelling using entropy and model fit measures. [PDF]
Li Y, Xiong X, Oravecz Z, Chow SM.
europepmc +1 more source
Model Fit Estimation for Multilevel Structural Equation Models. [PDF]
Rappaport LM, Amstadter AB, Neale MC.
europepmc +1 more source
Folder 9: Model engine data sheets and operating instructions, P - S, 1942, 1990, 1998
MK model products advertisement for model engines.
MK Model Products
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Does one model fit all mAbs? An evaluation of population pharmacokinetic models. [PDF]
van den Berg SPH +3 more
europepmc +1 more source
Relative Model Fit Does Not Predict Topological Accuracy in Single-Gene Protein Phylogenetics. [PDF]
Spielman SJ.
europepmc +1 more source

