Results 121 to 130 of about 10,310 (200)

Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene

Drug Testing and Analysis, Volume 18, Issue 8, Page 1097-1113, August 2026.
Eight metabolites for N‐pyrrolidino fluetonitazene were identified in vitro, three of which (M2, M6 and M8) were present in an authentic urine sample. M2 was the most abundant in vivo metabolite and is a common marker metabolite of nitazepyne‐type substances.
Severin Zemp, Gaia Alluisetti, Wolfgang Weinmann, Bettina Schrag, Frank Sporkert, Maurine Leclerc, Katharina Elisabeth Grafinger   +6 more
wiley   +1 more source

Active site design enables industrial scale H₂O₂ electrosynthesis with metal-free catalysts. [PDF]

Nat Commun
Yu A, Bi H, Joshua F, Lyons M, Rangavajjula A, Dhungana B, Park H, Cui Y, Ponnusamy VS, Kumar S, Liu S, Zhang Q, Du Y, Zhai L, Seal S, Guo J, Feng Z, Lin Z, Yang Y.   +18 more
europepmc   +1 more source

Longitudinal Tracking of Astrocyte Reactivity During the Development of Chronic Orofacial Neuropathic Pain Using [18F]‐SMBT‐1 Positron‐Emission Tomography

Glia, Volume 74, Issue 8, August 2026.
Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford, James W. M. Kang, OIivia I. Davanzo, Hyunsol Lim, Sabrina Salberg, Marissa Srgo, Crystal Li, Gaelle M. Emvalomenos, Bianca Jupp, Matthew Long, Wayne Noonan, Mohammad B. Haskali, Richelle Mychasiuk, Kevin A. Keay, Luke A. Henderson   +14 more
wiley   +1 more source

TET1 downregulation in the dorsal root ganglion and spinal cord is required for short-term sleep disturbance to delay surgical pain recovery. [PDF]

Br J Anaesth
Cao J, Wang PK, Xu B, Gu X, Pan Z, Cai W, Su S, Li Z, Delorenzo J, Bekker A, Hu H, Tao YX.   +11 more
europepmc   +1 more source

Morroniside Attenuates Doxorubicin‐Induced Cardiotoxicity by Activating the PI3K/AKT/Nrf2/HO‐1 Pathway to Inhibit Ferroptosis and Oxidative Stress

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Mor activates the PI3K/AKT pathway to promote Nrf2 nuclear translocation and HO‐1 expression, enhancing antioxidants, curbing Fe2+‐induced ROS/lipid peroxidation, suppressing ferroptosis, and alleviating Dox‐induced cardiotoxicity. ABSTRACT Cardiotoxicity induced by doxorubicin (Dox) significantly contributes to increased mortality among cancer ...
Zhi‐Hui Lin, Xing‐Yu Lin, Wen‐Jie Lu, Meng‐Qi Wu, Dong‐Yan Song, Rui‐Dong Cheng   +5 more
wiley   +1 more source

G-protein regulatory network governs receptor internalization dynamics. [PDF]

Proc Natl Acad Sci U S A
Rowe JB, Pandey S, Mayer RA, Ludlam WG, Drube J, Inoue A, Hoffmann C, Martemyanov KA.   +7 more
europepmc   +1 more source

Connecting models, networks, and experiments: Revisiting the role of viruses in marine carbon cycling

Limnology and Oceanography, Volume 71, Issue 8, August 2026.
Abstract The marine microbial food web is a key driver of global carbon cycling, mediating the production, consumption, and remineralization of organic matter in the ocean. Within this food web, viruses exert strong top‐down control by infecting and lysing both phytoplankton and heterotrophic bacteria.
Maxine Pruvôt, Bart Haegeman, Fabien Joux, David Demory   +3 more
wiley   +1 more source

Synthesis of High-Entropy Alloy Nanomaterials for Electrocatalytic Multi-Electron Transfer Reactions. [PDF]

ACS Nano
Meng X, Wang Y, Guo L, Hao F, Liu F, Wang J, Wang G, Shao M, Wang C, Huang X, Fan Z.   +10 more
europepmc   +1 more source

Attitudes Toward Homosexuality Among Jews and Arabs in Israel: An Empirical Study of Cultural and Personal Variables

Sexuality, Gender &Policy, Volume 9, Issue 3, August 2026.
ABSTRACT The study aimed to investigate the cultural and gender differences in the attitudes of Israeli Jews and Israeli Arabs toward homosexuality. A self‐reporting questionnaire was completed by 519 participants. A significant difference was discovered between Jewish and Arab individuals, with those who had prior familiarity with the lesbian, gay ...
Vered Ben David, Felix Kaplan
wiley   +1 more source

Activation dynamics of a water-soluble human mu-opioid receptor. [PDF]

J Biol Chem
Agyemang E, Van Wirt R, Walls C, Joseph TT, Tiruvadi-Krishnan S, Grothusen J, Zhang Q, Hicks A, Leite W, Osti NC, Mamontov E, O'Neill HM, Liu R, Lamichhane R.   +13 more
europepmc   +1 more source