From mouse to human: Fine mapping of quantitative trait loci in a model organism [PDF]
, 2000 Mary Sara McPeek
openalex +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Vital A Fish: A Critical Review of Zebrafish Models in Disease Scenario and Case Reports Screens
Laboratuvar Hayvanları Bilimi ve Uygulamaları DergisiVirtually every major medical advance of the last century and at still has depended upon research with animals. Zebrafish's journey from the ocean to the laboratory leads to major scientific breakthroughs.
Nurdan Filik
doaj +1 more source
Advanced Chinese Medicine, EarlyView.Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley +1 more source
«Ageing» Experiment Gravity effects during space flights upon aging and longevity of the living organisms: modeling the gravity of solar system planets [PDF]
, 2000 V.V. Frolkis, Kh.K. Muradian
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao +5 more
wiley +1 more source
CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani +11 more
wiley +1 more source
General model for nutritional responses of higher organisms.
, 1975 Paul H. Morgan +2 more
openalex +1 more source
Neurospora – Contributions of a Model Organism. Rowland H. Davis. Oxford University Press. 2000. 346 pages. Price £69.50. ISBN 0-19-512236-4. [PDF]
, 2001 John R. S. Fincham
openalex +1 more source
INF2‐Related Charcot–Marie–Tooth Disease in a Japanese Cohort: Genetic and Clinical Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background INF2 mutations cause focal segmental glomerulosclerosis (FSGS) and Charcot–Marie–Tooth disease (CMT). Accurate genetic diagnosis is critical, as INF2‐related FSGS is typically resistant to immunotherapy yet rarely recurs after transplantation, and its associated neuropathy can mimic treatable immune‐mediated disorders such as ...
Chikashi Yano +27 more
wiley +1 more source