Results 241 to 250 of about 1,700,235 (339)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Decentralized nonlinear model predictive control-based flock navigation with real-time obstacle avoidance in unknown obstructed environments. [PDF]

Front Robot AI
Gerdpratoom N, Yamamoto K.
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Coordinated distributed model predictive control for multi energy carrier systems. [PDF]

Sci Rep
El-Afifi MI, Eladl AA, El-Saadawi MM, Sedhom BE, Osman SF.   +4 more
europepmc   +1 more source

Model Predictive Control [PDF]

, 2017
openaire   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Digital twin syncing for autonomous surface vessels using reinforcement learning and nonlinear model predictive control. [PDF]

Sci Rep
Berg HS, Menges D, Tengesdal T, Rasheed A.   +3 more
europepmc   +1 more source

Optimization of a Free Cooling System Integrated with Cold Thermal Energy Storage in Data Center Based on Model Predictive Control

Xiang Ke, Zhiyong Tian, Nyuk Ling, Xinyu Chen, Yongqiang Luo, Yafeng Gao, Jianhua Fan, Qian Wang   +7 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

The potential of combined robust model predictive control and deep learning in enhancing control performance and adaptability in energy systems. [PDF]

Sci Rep
Lv X, Basem A, Hasani M, Sun P, Zhang J.
europepmc   +1 more source