Results 181 to 190 of about 3,666,543 (317)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Funding Liquidity Risk in a Quantitative Model of Systemic Stability [PDF]

We demonstrate how the introduction of liability-side feedbacks affects the properties of a quantitative model of systemic risk. The preliminary version of the model, which is still in its development phase, is based on detailed balance sheets for UK ...
Bruno Eklund, Gabriel Sterne, David Aikman, Nada Mora, Piergiorgio Alessandri, Prasanna Gai, Sujit Kapadia, Elizabeth Martin, Matthew Willison   +8 more
core  

Quantile of a Mixture with Application to Model Risk Assessment

Dependence Modeling, 2015
Bernard Carole, Vanduffel Steven
doaj   +1 more source

Multi-model risk assessment of pesticide residues in seasonal fruits based on integrated targeted/non-targeted screening: Implications for vulnerable populations. [PDF]

Food Chem X
Si W, Song Y, Guo C, Huang Z, Chen L, Xu F, Bai B, Huo K, Wang S.   +8 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Intraoperative Features Improve Model Risk Predictions After Coronary Artery Bypass Grafting. [PDF]

Ann Thorac Surg Short Rep
Potosnak W, Dufendach KA, Nagpal C, Kaczorowski DJ, Yoon P, Bonatti J, Miller JK, Dubrawski AW.   +7 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Risk Factors and Development of a Risk Prediction Model for PICC-Related Thrombosis in Radiotherapy Inpatients: A Single-Center Retrospective Cohort Study

Risk Management and Healthcare Policy
Qin-Mei Lin,1,* Qin-Lin Guo,2,* Zhuang-Bin Lin,3 Ai-Ying Chen,1 Zhen Chen,4 Qiu-Yan Zhang,2 Li-Yuan Chen,4 Bi-Hua Lin1 1Department of Outpatient Nursing, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, People’s Republic ...
Lin QM, Guo QL, Lin ZB, Chen AY, Chen Z, Zhang QY, Chen LY, Lin BH   +7 more
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The Intersections of COVID-19, HIV, and Race/Ethnicity: Machine Learning Methods to Identify and Model Risk Factors for Severe COVID-19 in a Large U.S. National Dataset. [PDF]

AIDS Behav
Kunz M, Rott KW, Hurwitz E, Kunisaki K, Sun J, Wilkins KJ, Islam JY, Patel R, Safo SE, National Covid Cohort Collaborative (N3C) Consortium.   +9 more
europepmc   +1 more source