Results 211 to 220 of about 7,849,545 (341)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Risk calculator of multimorbid risk of rehospitalization and death from heart failure: including the contribution of the gut microbiome. [PDF]

Eur J Prev Cardiol
Israr MZ, Salzano A, Zhan H, Voors AA, Ng LL, Suzuki T.   +5 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Model Summary for good fit of the data Statistics and Coefficients for Risks associated with supply chain performance in pharmaceutical company of Addis Ababa, Ethiopia, 2023 (N=172).

Dinku Mechal (21273002), Bekele Boche (12235967)   +1 more
openalex   +1 more source

Candidaemia and a risk predictive model for overall mortality: a prospective multicentre study [PDF]

, 2019
Caitlin Keighley, S. C-A. Chen, Deborah Marriott, A. L. Pope, Belinda Chapman, K. Kennedy, Narin Bak, N. Underwood, Heather L. Wilson, Kyle McDonald, Jai N. Darvall, Catriona Halliday, Sarah Kidd, Quoc Nguyen, Krispin Hajkowicz, Tania C. Sorrell, Sebastiaan J. van Hal, Monica A. Slavin   +17 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

ESO valuation under IFRS 2 - considerations of agency theory, risk aversion and the binomial model

, 2005
Antti Pirjetä, Antti Rautiainen
openalex   +1 more source

A7SEM as a Pre-Compliance Framework for Societal AI: A Systemic Model for Risk, Governance and Human–Machine Symmetry

Akarkach, Mounir
openalex   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Multimodal digital biopsy for preoperative prediction of occult peritoneal metastasis in gastric cancer. [PDF]

NPJ Digit Med
Chen S, Ding P, Yang Y, Ma S, Guo H, Han X, Yang J, Ma W, Meng N, Xia Z, Li X, Zhang L, Shi Y, Guo Z, Gao K, Gu R, Long H, Meng L, Zhao Q.   +18 more
europepmc   +1 more source