Results 221 to 230 of about 7,849,545 (341)
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Generating actionable insights to support point-of-care suicide risk decision-making in a safety-net healthcare system: a machine learning approach to predicting dynamic risk of intentional self-harm. [PDF]
Sarkar J +8 more
europepmc +1 more source
Asymptotic expansion of the risk of maximum likelihood estimator with respect to $\alpha$-divergence as a measure of the difficulty of specifying a parametric model -- with detailed proof [PDF]
Yo Sheena
openalex
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Towards Safer Freight Shunting: Integrating MILP and ML Classification Models in a Risk Management Framework [PDF]
BIGI, Federico +3 more
openalex
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source

