Results 191 to 200 of about 18,526,346 (319)

Effects of seepage and weak interlayer on the failure modes of surrounding rock: model tests and numerical analysis. [PDF]

R Soc Open Sci, 2019
Hu J, Wen H, Xie Q, Li B, Mo Q.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Research on the deformation mechanisms of accumulated landslides induced by different rain patterns based on flume model tests. [PDF]

PLoS One
Yi W, Luo H, Huang X, Zhu X, Wang Z, Li Y.   +5 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Model tests of dynamic response of modified lateritic soil embankments under combined action of wetting and vibration. [PDF]

Sci Rep
Han X, Qin X, He H, Yang G, Gong J.
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Full-Scale Model Tests of Two Box-Type Soil-Steel Structures with Different Crown and Haunch Radii. [PDF]

Materials (Basel)
Wu F, Liu B, Sun W, Sun H, Zhang S.
europepmc   +1 more source

Tree-Based Global Model Tests for Polytomous Rasch Models. [PDF]

Educ Psychol Meas, 2018
Komboz B, Strobl C, Zeileis A.
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Glutamic-acid grafted hyaluronic acid inhibits inflammatory factors via fibroblast and skin model tests. [PDF]

Skin Res Technol
Jiang FR, Wang S, Han D, Wei J, Wu YN, Liu Z.   +5 more
europepmc   +1 more source