Results 151 to 160 of about 7,715,827 (290)

Drug-Use Safety Enhancement Model-Theory and Application. [PDF]

Public Health Chall
Dunbar ET, Bartkowiak A, Brennan AL.
europepmc   +1 more source

Analysis of molecular dynamics simulations of 10-residue peptide, chignolin, using statistical mechanics: Relaxation mode analysis and three-dimensional reference interaction site model theory. [PDF]

Biophys Physicobiol, 2019
Maruyama Y, Takano H, Mitsutake A.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A New Approach for Estimating Liver IVIM Fast Diffusion Coefficient in Two-Compartment Model and Fast Diffusion Fraction in Three-Compartment Model: Theory and In Vivo Validation of Two Centers' Data. [PDF]

NMR Biomed
Ma FZ, Wáng YXJ.
europepmc   +1 more source

Model theory and the cardinal numbers p and t. [PDF]

Proc Natl Acad Sci U S A, 2013
Moore JT.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Marine Propulsors and Current Turbines: State of the Art and Current Challenges

International Journal of Rotating Machinery, 2012
Yin Lu Young, Moustafa Abdel-Maksoud, Jules W. Lindau, Francesco Salvatore, Moon Chan Kim   +4 more
doaj   +1 more source

A Machine Learning Model Based on Counterfactual Theory for Treatment Decision of Hepatocellular Carcinoma Patients

Journal of Hepatocellular Carcinoma
Xiaoqin Wei,1,* Fang Wang,2,* Ying Liu,3 Zeyong Li,4 Zhong Xue,2 Mingyue Tang,5 Xiaowen Chen1 1School of Medical Imaging, North Sichuan Medical College, Nanchong City, Sichuan Province, People’s Republic of China; 2Department of Research and ...
Wei X, Wang F, Liu Y, Li Z, Xue Z, Tang M, Chen X   +6 more
doaj  

A new probabilistic model: Theory, simulation and applications to sports and failure times data. [PDF]

Heliyon
Tang X, Seong JT, Alharbi R, Mutairi AA, Nasr SG.   +4 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source