Results 11 to 20 of about 12,063,985 (329)
The risk of type 2 oral polio vaccine use in post-cessation outbreak response
Background Wild type 2 poliovirus was last observed in 1999. The Sabin-strain oral polio vaccine type 2 (OPV2) was critical to eradication, but it is known to revert to a neurovirulent phenotype, causing vaccine-associated paralytic poliomyelitis.
Kevin A. McCarthy+4 more
doaj +1 more source
Among model comprehension tools, model slicers are tools that extract a subset from a model, for a specific purpose. Model slicers are tools that let modelers rapidly gather relevant knowledge from large models. However, existing slicers are dedicated to one modeling language. This is an issue when we observe that new domain specific modeling languages
Blouin, Arnaud+3 more
openaire +4 more sources
Background While bed nets and insecticide spraying have had significant impact on malaria burden in many endemic regions, outdoor vector feeding and insecticide resistance may ultimately limit their contribution to elimination and control campaigns ...
Prashanth Selvaraj+4 more
doaj +1 more source
Background The 3D organization of the chromatin fiber in cell nuclei plays a key role in the regulation of gene expression. Genome-wide techniques to score DNA-DNA contacts, such as Hi-C, reveal the partitioning of chromosomes into epigenetically defined
Xian Hao+6 more
doaj +1 more source
What is required to end the AIDS epidemic as a public health threat by 2030? the cost and impact of the fast-track approach [PDF]
In 2011 a new Investment Framework was proposed that described how the scale-up of key HIV interventions could dramatically reduce new HIV infections and AIDS-related deaths in low and middle income countries by 2015.
Fast Track Modeling Working Group
core +1 more source
Business Models as Models [PDF]
Drawing on research undertaken in the history and philosophy of science, with particular reference to the extensive literature which discusses the use of models in biology and economics, we explore the question ‘Are Business Models useful?’ We point out that they act as various forms of model: to provide means to describe and classify businesses; to ...
Mary S. Morgan, Charles Baden-Fuller
openaire +3 more sources
Background Our aim was to extend traditional parametric models used to extrapolate survival in cost-effectiveness analyses (CEAs) by integrating individual-level patient data (IPD) from a clinical trial with estimates from experts regarding long-term ...
Dieter Ayers+5 more
doaj +1 more source
Deviation Distribution Features of CMA-GFS Cloud Prediction
Clouds play a vital role in weather, climate system and the atmospheric water cycle. The diagnosis and evaluation of numerical model prediction results is important for numerical model research and development. Reasonable diagnosis and evaluation methods
Li Zhe+5 more
doaj +1 more source
Introduction Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with memory, cognitive, and behavioral deficits, and brings significant economic burden on caregivers and healthcare systems.
Amir Abbas Tahami Monfared+6 more
doaj +1 more source
Introduction Alzheimer’s disease (AD), a progressive neurodegenerative disease, is the main cause of dementia and one of the leading causes of death for elderly people in the USA.
Amir Abbas Tahami Monfared+6 more
doaj +1 more source