Results 11 to 20 of about 7,875,864 (298)

Modeling modeling modeling [PDF]

open access: yesSoftware & Systems Modeling, 2010
Model-driven engineering and model-based approaches have permeated all branches of software engineering to the point that it seems that we are using models, as Molière's Monsieur Jourdain was using prose, without knowing it. At the heart of modeling, there is a relation that we establish to represent something by something else. In this paper we review
Muller, Pierre-Alain   +3 more
openaire   +2 more sources

Modeling Model Uncertainty [PDF]

open access: yesJournal of the European Economic Association, 2002
Recently there has been a great deal of interest in studying monetary policy under model uncertainty. We develop new methods to analyze different sources of uncertainty in one coherent structure, which is useful for policy decisions. We show how to estimate the size of the uncertainty based on time series data, and how to incorporate this uncertainty ...
Onatski, Alexei, Williams, Noah
openaire   +6 more sources

Structured expert elicitation to inform long-term survival extrapolations using alternative parametric distributions: a case study of CAR T therapy for relapsed/ refractory multiple myeloma

open access: yesBMC Medical Research Methodology, 2022
Background Our aim was to extend traditional parametric models used to extrapolate survival in cost-effectiveness analyses (CEAs) by integrating individual-level patient data (IPD) from a clinical trial with estimates from experts regarding long-term ...
Dieter Ayers   +5 more
doaj   +1 more source

Business Models as Models [PDF]

open access: yesLong Range Planning, 2010
Drawing on research undertaken in the history and philosophy of science, with particular reference to the extensive literature which discusses the use of models in biology and economics, we explore the question ‘Are Business Models useful?’ We point out that they act as various forms of model: to provide means to describe and classify businesses; to ...
Baden-Fuller, C., Morgan, M.S.
openaire   +4 more sources

Super-resolution visualization and modeling of human chromosomal regions reveals cohesin-dependent loop structures

open access: yesGenome Biology, 2021
Background The 3D organization of the chromatin fiber in cell nuclei plays a key role in the regulation of gene expression. Genome-wide techniques to score DNA-DNA contacts, such as Hi-C, reveal the partitioning of chromosomes into epigenetically defined
Xian Hao   +6 more
doaj   +1 more source

Estimated Societal Value of Lecanemab in Patients with Early Alzheimer’s Disease Using Simulation Modeling

open access: yesNeurology and Therapy, 2023
Introduction Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with memory, cognitive, and behavioral deficits, and brings significant economic burden on caregivers and healthcare systems.
Amir Abbas Tahami Monfared   +6 more
doaj   +1 more source

Modeling Model Slicers [PDF]

open access: yes, 2011
Among model comprehension tools, model slicers are tools that extract a subset from a model, for a specific purpose. Model slicers are tools that let modelers rapidly gather relevant knowledge from large models. However, existing slicers are dedicated to one modeling language. This is an issue when we observe that new domain specific modeling languages
Blouin, Arnaud   +3 more
openaire   +3 more sources

Deviation Distribution Features of CMA-GFS Cloud Prediction

open access: yes应用气象学报, 2022
Clouds play a vital role in weather, climate system and the atmospheric water cycle. The diagnosis and evaluation of numerical model prediction results is important for numerical model research and development. Reasonable diagnosis and evaluation methods
Li Zhe   +5 more
doaj   +1 more source

A Path to Improved Alzheimer’s Care: Simulating Long-Term Health Outcomes of Lecanemab in Early Alzheimer’s Disease from the CLARITY AD Trial

open access: yesNeurology and Therapy, 2023
Introduction Alzheimer’s disease (AD), a progressive neurodegenerative disease, is the main cause of dementia and one of the leading causes of death for elderly people in the USA.
Amir Abbas Tahami Monfared   +6 more
doaj   +1 more source

Continuous Integration for Concurrent MOOSE Framework and Application Development on GitHub

open access: yesJournal of Open Research Software, 2015
For the past several years, Idaho National Laboratory’s MOOSE framework team has employed modern software engineering techniques (continuous integration, joint application/framework source code repos- itories, automated regression testing, etc.) in ...
Andrew E. Slaughter   +5 more
doaj   +1 more source

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