Results 11 to 20 of about 1,436,254 (268)

Modeling modeling modeling [PDF]

open access: yesSoftware & Systems Modeling, 2010
Model-driven engineering and model-based approaches have permeated all branches of software engineering to the point that it seems that we are using models, as Molière's Monsieur Jourdain was using prose, without knowing it. At the heart of modeling, there is a relation that we establish to represent something by something else. In this paper we review
Muller, Pierre-Alain   +3 more
openaire   +2 more sources

Modeling in the large: model libraries [PDF]

open access: yesSoftware and Systems Modeling, 2021
Software and systems modeling (2021).
Jeff Gray 0001, Bernhard Rumpe
openaire   +2 more sources

MODELING MODELING [PDF]

open access: yesJournal of the Experimental Analysis of Behavior, 1999
Models are tools; they need to fit both the hand and the task. Presence or absence of a feature such as a pacemaker or a cascade is not in itself good. Or bad. Criteria for model evaluation involve benefit‐cost ratios, with the numerator a function of the range of phenomena explained, goodness of fit, consistency with other nearby models, and ...
openaire   +2 more sources

Modeling Model Slicers [PDF]

open access: yes, 2011
Among model comprehension tools, model slicers are tools that extract a subset from a model, for a specific purpose. Model slicers are tools that let modelers rapidly gather relevant knowledge from large models. However, existing slicers are dedicated to one modeling language. This is an issue when we observe that new domain specific modeling languages
Blouin, Arnaud   +3 more
openaire   +2 more sources

Structured expert elicitation to inform long-term survival extrapolations using alternative parametric distributions: a case study of CAR T therapy for relapsed/ refractory multiple myeloma

open access: yesBMC Medical Research Methodology, 2022
Background Our aim was to extend traditional parametric models used to extrapolate survival in cost-effectiveness analyses (CEAs) by integrating individual-level patient data (IPD) from a clinical trial with estimates from experts regarding long-term ...
Dieter Ayers   +5 more
doaj   +1 more source

Super-resolution visualization and modeling of human chromosomal regions reveals cohesin-dependent loop structures

open access: yesGenome Biology, 2021
Background The 3D organization of the chromatin fiber in cell nuclei plays a key role in the regulation of gene expression. Genome-wide techniques to score DNA-DNA contacts, such as Hi-C, reveal the partitioning of chromosomes into epigenetically defined
Xian Hao   +6 more
doaj   +1 more source

Estimated Societal Value of Lecanemab in Patients with Early Alzheimer’s Disease Using Simulation Modeling

open access: yesNeurology and Therapy, 2023
Introduction Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with memory, cognitive, and behavioral deficits, and brings significant economic burden on caregivers and healthcare systems.
Amir Abbas Tahami Monfared   +6 more
doaj   +1 more source

Deviation Distribution Features of CMA-GFS Cloud Prediction

open access: yes应用气象学报, 2022
Clouds play a vital role in weather, climate system and the atmospheric water cycle. The diagnosis and evaluation of numerical model prediction results is important for numerical model research and development. Reasonable diagnosis and evaluation methods
Li Zhe   +5 more
doaj   +1 more source

Business Models as Models [PDF]

open access: yesLong Range Planning, 2010
Drawing on research undertaken in the history and philosophy of science, with particular reference to the extensive literature which discusses the use of models in biology and economics, we explore the question ‘Are Business Models useful?’ We point out that they act as various forms of model: to provide means to describe and classify businesses; to ...
Baden-Fuller, C., Morgan, M.S.
openaire   +3 more sources

A Path to Improved Alzheimer’s Care: Simulating Long-Term Health Outcomes of Lecanemab in Early Alzheimer’s Disease from the CLARITY AD Trial

open access: yesNeurology and Therapy, 2023
Introduction Alzheimer’s disease (AD), a progressive neurodegenerative disease, is the main cause of dementia and one of the leading causes of death for elderly people in the USA.
Amir Abbas Tahami Monfared   +6 more
doaj   +1 more source

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