Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Visualizing epidemiological models for policy: design principles for effective communication. [PDF]
Hadley L +8 more
europepmc +1 more source
Sociology: methodology, methods, mathematical modeling (Sociology: 4M)
openalex +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
RA-BiMENet: Continuous-Time 4D Medical Image Interpolation via Relation-Aware Bi-Directional Motion Estimation. [PDF]
Li L, Lyu J.
europepmc +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
An integrated method for state of charge estimation, lifetime prediction, and reliability assessment of Lithium-ion batteries under thermal and dynamic conditions. [PDF]
Mobasheri P, Aranizadeh A, Vahidi B.
europepmc +1 more source
Household and skill disaggregation in multi-sectoral models of the Scottish economy
Andrew Ross
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The Abundance of Low Energy Cosmic Ray Boron and Nitrogen Nuclei Measured at Voyager 1 Beyond the Heliopause, Where Do They All Come From? An Interpretation Using a Leaky Box Galactic Propagation Model [PDF]
W. R. Webber
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