Results 251 to 260 of about 12,063,985 (329)

The future of pandemic modeling in support of decision making: lessons learned from COVID-19. [PDF]

BMC Glob Public Health
Moran KR, Lopez T, Del Valle SY.
europepmc   +1 more source

THE ACTIVE AREA IN COURSE OF EXCITATION CONDUCTION (OBSERVATIONS ON LILLIE'S NERVE MODEL)

, 1948
Kazumi Yamagiwa
openalex   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Uses, Abuses, and Future of Great Lakes Modeling: Report of the Modeling Task Force, February, 1986, Windsor, Ontario [PDF]

, 1986
Great Lakes Science Advisory Board. Modeling Task Force
core   +1 more source

Correction: Semiparametric modeling for the cardiometabolic risk index and individual risk factors in the older adult population: A novel proposal. [PDF]

PLoS One
Tadger P, Alfonso-Mora ML, Díaz-Vidal D, Quino-Ávila AC, Méndez JL, Sandoval-Cuellar C, Monsalve-Jaramillo E, Giné-Garriga M.   +7 more
europepmc   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Exploring the latent space of transcriptomic data with topic modeling. [PDF]

NAR Genom Bioinform
Valle F, Caselle M, Osella M.
europepmc   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

EcoNicheS: enhancing ecological niche modeling, niche overlap and connectivity analysis using the shiny dashboard and R package. [PDF]

PeerJ
Sunny A, Marmolejo C, Vidal-López R, Falconi-Briones FA, Cuervo-Robayo ÁP, Bolom-Huet R.   +5 more
europepmc   +1 more source

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

Molecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger, Dorin Bar‐Ziv, Harriet Kluger   +2 more
wiley   +1 more source