Results 271 to 280 of about 12,063,985 (329)

Potential Meets Practicality: AI's Current Impact on the Evidence Generation and Synthesis Pipeline in Health Economics. [PDF]

Clin Transl Sci
Naylor NR, Hummel N, de Moor C, Kadambi A.   +3 more
europepmc   +1 more source

Guide to Sowerby's models of British fungi in the Department of Botany, British Museum (Natural History) / by Worthington G. Smith.

, 1898
WORTHINGTON G. SMITH
openalex   +2 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Development and effectiveness verification of AI education data sets based on constructivist learning principles for enhancing AI literacy. [PDF]

Sci Rep
Kim SK, Kim TY, Kim K.
europepmc   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Analysis of Prognostic Factors for Drilling Drainage Surgery in Patients with Hypertensive Intracerebral Hemorrhage and Development of a Predictive Nomogram. [PDF]

Risk Manag Healthc Policy
Gu J, Dai L, Hu W, Xie C, Ren X, Huang J.   +5 more
europepmc   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Don't Miss the Forest for the Trees: How Abstracting Nature Can Get Us Closer to Our Goals. [PDF]

Glob Chang Biol
Lawlor J.
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Collaborative engagement with vector control stakeholders is key to enhance the utility of vector-borne disease models. [PDF]

Parasit Vectors
Brown HE, Wrench E, Wolfe K, Moore TC, Tangena JA, Sedda L.   +5 more
europepmc   +1 more source