Results 291 to 300 of about 12,063,985 (329)

Bayesian modeling with locally adaptive prior parameters in small animal imaging. [PDF]

Front Nucl Med
Zhang M, Aykroyd RG, Tsoumpas C.
europepmc   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Promoting Employee Organizational Citizenship Behavior (OCB) in Small- and Medium-Sized Enterprises: A Cognitive and Affective Perspective on Ethical Leadership. [PDF]

Behav Sci (Basel)
Su W, Hahn J.
europepmc   +1 more source

Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells

FEBS Open Bio, EarlyView.
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda, Hiroshi Iwakura, Takuya Ensho, Mika Bando‐Shimizu, Asako Doi, Norihiko Matsutani, Shuhei Morita, Hidefumi Inaba, Hiroyuki Ariyasu, Naoki Fukuda, Keiji Hayata, Toshiyasu Ojima, Masahiro Nishi, Taka‐aki Matsuoka, Hiroki Yamaue, Takashi Akamizu   +15 more
wiley   +1 more source

Retraction: Impact of the hydraulic fracturing on indoor radon concentrations in Ohio: a multilevel modeling approach. [PDF]

Front Public Health
Frontiers Editorial Office.
europepmc   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Perspective improvement of regional air pollution burden of disease estimation by machine intelligence. [PDF]

Front Public Health
Kuo CP, Fu JS, Liu Y.
europepmc   +1 more source

Predicting reverse-bound peptide conformations in MHC Class II with PANDORA. [PDF]

Front Immunol
Rademaker DT, Parizi FM, van Vreeswijk M, Eerden S, Marzella DF, Xue LC.   +5 more
europepmc   +1 more source

Correction: Transforming landscapes: Decoding the impact of universities on urbanization using advanced modeling and perception analysis. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

Effects of Climate Change Scenarios on Population and Distribution Pattern of Tree-Ferns in Nepal. [PDF]

Ecol Evol
Kunwar RM, Khadka D, Thapa-Magar K, Adhikari B, Kutal DH, Ghimire R, Kafle KR, Baral S, Thapa GJ, Bhandari A.   +9 more
europepmc   +1 more source