Results 71 to 80 of about 33,284,612 (360)
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2021 The success of applications of physiologically‐based pharmacokinetic (PBPK) modeling in drug development and drug labeling has triggered regulatory agencies to demand rigorous demonstration of the predictive capability of the specific PBPK platform for a
Sebastian Frechen +7 more
doaj +1 more source
CMA Global Ensemble Prediction Using Singular Vectors from Background Field
应用气象学报, 2022 China Meteorological Administration Global Ensemble Prediction System (CMA-GEPS) adopts singular vector method to generate initial perturbations.
Huo Zhenhua +3 more
doaj +1 more source
Modeling of species distributions with Maxent: new extensions and a comprehensive evaluation
, 2008 Accurate modeling of geographic distributions of species is crucial to various applications in ecology and conservation. The best performing techniques often require some parameter tuning, which may be prohibitively time-consuming to do separately for ...
Steven J. Phillips, Miroslav Dudík
semanticscholar +1 more source
Statsmodels: Econometric and Statistical Modeling with Python
SciPy, 2010 Statsmodels is a library for statistical and econometric analysis in Python. This paper discusses the current relationship between statistics and Python and open source more generally, outlining how the statsmodels package fills a gap in this ...
Skipper Seabold, Josef Perktold
semanticscholar +1 more source
Ecological Questions, 2008 When searching for nature rules we encounter a fundamental difficulty: for technical reasons we are not able to investigate the whole Nature - we have to explore its sections i.e. empirical systems (structures). However, even then it might happen that the system is too complex and its comprehensive, direct investigation is impossible.
openaire +3 more sources
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Nature CommunicationsThe intricate hydrogen-bonded network of water gives rise to various structures with anomalous properties at different thermodynamic conditions. Nanoconfinement can further modify the water structure and properties, and induce specific water motifs ...
Aran Lamaire +5 more
doaj +1 more source
Abstract and Applied Analysis, 2020 The linear complementarity problem is receiving a lot of attention and has been studied extensively. Recently, El foutayeni et al. have contributed many works that aim to solve this mysterious problem.
Yamna Achik +4 more
doaj +1 more source
Scientific Reports, 2022 SARS-CoV-2 is the pathogen responsible for COVID-19 that has claimed over six million lives as of July 2022. The severity of COVID-19 motivates a need to understand how it could evolve to escape potential treatments and to find ways to strengthen ...
Jonathan E. Barnes +3 more
doaj +1 more source