Results 71 to 80 of about 14,236,793 (352)

The Hopfield model and its role in the development of synthetic biology [PDF]

open access: yes, 2007
Neural network models make extensive use of concepts coming from physics and engineering. How do scientists justify the use of these concepts in the representation of biological systems?
Loettgers, Andrea
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

A formal theory of conceptual modeling universals [PDF]

open access: yes, 2004
Conceptual Modeling is a discipline of great relevance to several areas in Computer Science. In a series of papers [1,2,3] we have been using the General Ontological Language (GOL) and its underlying upper level ontology, proposed in [4,5], to evaluate ...
Guizzardi, Giancarlo   +2 more
core   +3 more sources

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

The effect of mutations on binding interactions between the SARS-CoV-2 receptor binding domain and neutralizing antibodies B38 and CB6

open access: yesScientific Reports, 2022
SARS-CoV-2 is the pathogen responsible for COVID-19 that has claimed over six million lives as of July 2022. The severity of COVID-19 motivates a need to understand how it could evolve to escape potential treatments and to find ways to strengthen ...
Jonathan E. Barnes   +3 more
doaj   +1 more source

Study on neighborhood ensemble probability forecasting method of precipitation for CMA-REPS system

open access: yes暴雨灾害, 2023
In this paper, based on the regional ensemble CMA-REPS V3.1 system, the algorithm for the neighborhood ensemble probability method of precipitation is optimized.
Zhili LIU   +3 more
doaj   +1 more source

Kernel Spectral Curvature Clustering (KSCC)

open access: yes, 2009
Multi-manifold modeling is increasingly used in segmentation and data representation tasks in computer vision and related fields. While the general problem, modeling data by mixtures of manifolds, is very challenging, several approaches exist for ...
Atev, S., Chen, G., Lerman, G.
core   +2 more sources

Modeling the purposes of models

open access: yes, 2012
Today, the purpose of a model is often kept implicit. The lack of explicit statements about a model's purpose hinders both its creation and its (re)use. In this paper, we adapt two goal modeling techniques, the Goal-Question-Metric paradigm and KAOS, an intentional modeling language, so that the purpose of a model can be explicitly stated and ...
Jeanneret, Cédric   +2 more
openaire   +2 more sources

Is the Voter Model a Model for Voters? [PDF]

open access: yesPhysical Review Letters, 2014
The voter model has been studied extensively as a paradigmatic opinion dynamics' model. However, its ability for modeling real opinion dynamics has not been addressed. We introduce a noisy voter model (accounting for social influence) with agents' recurrent mobility (as a proxy for social context), where the spatial and population diversity are taken ...
Fernández-Gracia, Juan   +4 more
openaire   +4 more sources

Supporting Survivor‐Centered Care Through Digital Health Integration

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak   +15 more
wiley   +1 more source

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