Results 91 to 100 of about 525,813 (267)

The Modeling Process for Stage Models

open access: yesJournal of Organizational Computing and Electronic Commerce, 2010
This is the authors' final and acceptet version of the article, post refereeing.
Hans Solli-Sæther, Petter Gottschalk
openaire   +2 more sources

Modeling Patterns of Population Exposure With a Multiscale Framework Utilizing LOTOS‐EUROS Chemical Transport Model, Mobility Surveys and Particulate Toxicity

open access: yesGeoHealth
The present study proposes a high‐resolution, multi‐component framework to estimate human exposure to air pollution in tropical urban environments, addressing complex topography and limited historical mobility and exposure data. This framework is applied
Valeria Solórzano‐Araque   +8 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Note on Model Complete Models and Generic Models [PDF]

open access: yesProceedings of the American Mathematical Society, 1972
We prove that there are many maximum model complete (= generic) models, and that there exists an (uncountable) theory with no generic models.
openaire   +2 more sources

Insights from quantitative analysis and mathematical modelling on the proposed WHO 2030 goals for soil-transmitted helminths [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
Soil-transmitted helminths (STHs) are a group of parasitic worms that infect humans, causing a wide spectrum of disease, notably anaemia, growth retardation, and delayed cognitive development.
NTD Modelling Consortium discussion group on soil-transmitted helminths
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Akka as a tool for modelling and managing a smart grid system

open access: yesJournal of Edge Computing
The article addresses big data processing challenges, fault tolerance, and consumer interaction in a smart grid network management system. It analyses the use of Akka for agent-based modelling of smart grid systems, which enables the creation of ...
Mykola Yaroshynskyi   +4 more
doaj   +1 more source

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