Results 201 to 210 of about 10,618,209 (336)

Data-driven queueing modelling: a simulation case study of emergency department crowding. [PDF]

BMJ Health Care Inform
Wartelle A, Mourad-Chehade F, Yalaoui F, Laplanche D, Sanchez S.   +4 more
europepmc   +1 more source

Tropical Cyclone Simulation and Response to CO2 Doubling in the GFDL CM2.5 High-Resolution Coupled Climate Model [PDF]

, 2014
Hyeong‐Seog Kim, Gabriel A. Vecchi, Thomas R. Knutson, W. Anderson, Thomas L. Delworth, Anthony Rosati, Fanrong Zeng, Ming Zhao   +7 more
openalex   +1 more source

Screening membraneless organelle participants with machine-learning models that integrate multimodal features

, 2022
Zhaoming Chen, Chao Hou, Liang Wang, Chunyu Yu, Taoyu Chen, Boyan Shen, Yaoyao Hou, Pilong Li, Tingting Li   +8 more
openalex   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses [PDF]

, 2016
Natividad Gomez-Roman, Katrina H. Stevenson, Lesley Gilmour, Graham Hamilton, Anthony J. Chalmers   +4 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A Longitudinal Analysis of a Motor Skill Parameter in Junior Triathletes from a Wearable Sensor. [PDF]

Sensors (Basel)
Chesher SM, Chapman DW, Liew B, Rosalie SM, Riddell H, Charlton PC, Netto KJ.   +6 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Estimating the value of face coverings during the COVID-19 epidemic: a dynamic causal modelling study. [PDF]

BMJ Public Health
Bowie C, Costello A, Friston K.
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source