Results 121 to 130 of about 7,167,330 (247)

Meta-dynamical adaptive systems and their applications to a fractal algorithm and a biological model

, 2005
Emmanuel Moulay, Marc Baguelin
openalex   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Do fungi look like macroparasites? Quantifying the patterns and mechanisms of aggregation for host-fungal parasite relationships. [PDF]

Proc Biol Sci
Schrock SAR, Walsman JC, DeMarchi J, LeSage EH, Ohmer MEB, Rollins-Smith LA, Briggs CJ, Richards-Zawacki CL, Woodhams DC, Knapp RA, Smith TC, Haddad CFB, Becker CG, Johnson PTJ, Wilber MQ.   +14 more
europepmc   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Incremental modelling and analysis of biological systems with fuzzy hybrid Petri nets. [PDF]

Brief Bioinform
Assaf G, Liu F, Heiner M.
europepmc   +1 more source

Mathematical and Computer Simulation of the Biological Life Support System Module 2/2. Verification of the model and scenarios [PDF]

, 2009
Gubanov Vladimir G., Barkhatov Yury V., Manukovsky Nikolai S., Ushakova Sofya A., Gribovskaya Iliada V., Alexander A. Tikhomirov, Degermendzhy Andrey G., Christophe Lasseur   +7 more
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Enhanced metabolomic predictions using concept drift analysis: identification and correction of confounding factors. [PDF]

Bioinform Adv
Schwarzerova J, Olesova D, Jureckova K, Kvasnicka A, Kostoval A, Friedecky D, Sekora J, Pomenkova J, Provaznik V, Popelinsky L, Weckwerth W.   +10 more
europepmc   +1 more source

Theoretical and in silico modeling of biological systems : from protein structure prediction to cellular dynamics [PDF]

, 2009
Bogdan Barz
openalex   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source