Results 131 to 140 of about 7,167,330 (247)

Assessment of uncertainty quantification in universal differential equations. [PDF]

Philos Trans A Math Phys Eng Sci
Schmid N, Fernandes Del Pozo D, Waegeman W, Hasenauer J.   +3 more
europepmc   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Discovering governing equations of biological systems through representation learning and sparse model discovery. [PDF]

NAR Genom Bioinform
Sadria M, Swaroop V.
europepmc   +1 more source

Modeling of Biological Intelligence for SCM System Optimization [PDF]

, 2011
Shengyong Chen, Yu‐Jun Zheng, Carlo Cattani, Wanliang Wang   +3 more
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Computational modelling of CAR T-cell therapy: from cellular kinetics to patient-level predictions. [PDF]

EBioMedicine
Murias-Closas A, Prats C, Calvo G, López-Codina D, Olesti E.   +4 more
europepmc   +1 more source

GemCell: A generic platform for modeling multi-cellular biological systems

, 2007
Hila Amir-Kroll, Avital Sadot, Irun R. Cohen, David Harel   +3 more
openalex   +1 more source

Modelling biological and chemically induced precipitation of calcium phosphate in enhanced biological phosphorus removal systems [PDF]

, 2011
R. Barat, Tatiana Montoya, A. Seco, J. Ferrer   +3 more
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Energy-based modelling of single actin filament polymerization using bond graphs. [PDF]

J R Soc Interface
Gawthrop PJ, Pan M, Rajagopal V.
europepmc   +1 more source