Results 161 to 170 of about 7,167,330 (247)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

CompSafeNano project: NanoInformatics approaches for safe-by-design nanomaterials. [PDF]

Comput Struct Biotechnol J
Zouraris D, Mavrogiorgis A, Tsoumanis A, Saarimäki LA, Del Giudice G, Federico A, Serra A, Greco D, Rouse I, Subbotina J, Lobaskin V, Jagiello K, Ciura K, Judzinska B, Mikolajczyk A, Sosnowska A, Puzyn T, Gulumian M, Wepener V, Martinez DST, Petry R, El Yamani N, Rundén-Pran E, Murugadoss S, Shaposhnikov S, Minadakis V, Tsiros P, Sarimveis H, Longhin EM, SenGupta T, Olsen AH, Skakalova V, Hutar P, Dusinska M, Papadiamantis AG, Gheorghe LC, Reilly K, Brun E, Ullah S, Cambier S, Serchi T, Tämm K, Lorusso C, Dondero F, Melagrakis E, Fraz MM, Melagraki G, Lynch I, Afantitis A.   +48 more
europepmc   +1 more source

Modelling and predicting the biological effects of nanomaterials

SAR and QSAR in environmental research (Print), 2014
David A. Winkler, F. Burden, Bing Yan, Ralph Weissleder, C. Tassa, Stanley Y. Shaw, V. Epa   +6 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Improving risk analysis of the environmental drivers of the spillover, emergence/re-emergence and spread of Crimean-Congo haemorrhagic fever virus, Marburg virus and Middle East respiratory syndrome coronavirus in the East Africa Region. [PDF]

BMJ Glob Health
Ajumobi O, Davis M, George CM, Rosman L, Von Dobschuetz S, Watson C, Nuzzo JB.   +6 more
europepmc   +1 more source

A mathematical model for the interpretation of nuclear bomb test derived 14C incorporation in biological systems

, 2009
Samuel Bernard, Jonas Frisén, Kirsty L. Spalding   +2 more
openalex   +2 more sources

CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability

Molecular Oncology, EarlyView.
Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki, Rose L. Jady‐Clark, Eileen E. Parkes   +2 more
wiley   +1 more source

Insights into silicon cycling from ice sheet to coastal ocean from isotope geochemistry. [PDF]

Commun Earth Environ
Hendry KR, Sales de Freitas F, Arndt S, Beaton A, Friberg L, Hatton JE, Hawkings JR, Jones RL, Krause JW, Meire L, Ng HC, Pryer H, Tingey S, van de Velde SJ, Wadham J, Wang T, Woodward EMS.   +16 more
europepmc   +1 more source

How to learn new and interesting things from model systems based on “exotic” biological species

, 2009
John M. Sedivy
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source