Results 201 to 210 of about 6,631,455 (355)

Modeling complex biological systems: Tackling the parameter curse through evolution

, 2021
paulien Hogeweg
openalex   +2 more sources

Fractional-Order Bioimpedance Modelling for Early Detection of Tissue Freezing in Cryogenic and Thermal Medical Applications. [PDF]

Sensors (Basel)
Vaquero-Gallardo N, Martínez-García H, Millán-Blasco O.   +2 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Safe and sustainable by design with ML/AI: A transformative approach to advancing nanotechnology. [PDF]

Beilstein J Nanotechnol
Melagraki G.
europepmc   +1 more source

Modelling biological modularity with CellML.

IET Systems Biology, 2008
M. Cooling, Peter Hunter, Edmund J. Crampin   +2 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Extending Gd(III)-Nitroxide Deer Methodology from Model Systems to Biological Applications

, 2014
Luca Garbuio
openalex   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

MxlPy-Python package for mechanistic learning and hybrid modelling in life science. [PDF]

Bioinform Adv
van Aalst M, Nies T, Pfennig T, Matuszyńska A.   +3 more
europepmc   +1 more source

Stochastic Modeling and Statistical Properties of Biological Systems Inferred from Omics Data [PDF]

, 2017
Claudia Sala
openalex   +1 more source