Results 221 to 230 of about 6,631,455 (355)

The LEGACY Program: A Falsifiable Framework for the Scientific Investigation of Anomalous Biological, Fabrication, and Cultural Systems through the Janus Quantum Topology Model ("Supplementary Files: Autopsy Protocol V2")

Lux Ferox Research Collective, François Mathieu   +1 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Advances in Cytotoxicity Testing: From In Vitro Assays to In Silico Models. [PDF]

Int J Mol Sci
Ziemba B.
europepmc   +1 more source

Robustness of mathematical models for biological systems

, 2004
Tianhai Tian
openalex   +2 more sources

WEST: modelling biological wastewater treatment

, 2003
H. Vanhooren, J. Meirlaen, Y. Amerlinck, F. Claeys, H. Vangheluwe, P. Vanrolleghem   +5 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Towards time-resolved multiscale and multimodal imaging. [PDF]

Npj Imaging
Chen J.
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Computational Methods for Identification and Modelling of Complex Biological Systems

Complexity, 2019
Alejandro F. Villaverde, Carlo Cosentino, Attila Gábor, Gábor Szederkényi   +3 more
doaj   +1 more source

In Vivo Prostate Cancer Modelling: From the Pre-Clinical to the Clinical Setting. [PDF]

Life (Basel)
Nascimento-Gonçalves E, Azevedo T, Medeiros C, Faustino-Rocha AI.   +3 more
europepmc   +1 more source