Results 261 to 270 of about 6,631,455 (355)

Insights from Molecular Simulations and Multi-Scale Mathematical Modeling of Biological Systems /

, 2014
Vincent Tyler Metzger
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Artificial Intelligence for Natural Products Drug Discovery in Neurodegenerative Therapies: A Review. [PDF]

Biomolecules
Fontanella F, D'Alessandro T, Nardone E, De Stefano C, Vicidomini C, Roviello GN.   +5 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Mathematical Modeling of Local Drug Delivery in the Oral Cavity: From Release Kinetics to Mini-PBPK and Local PK/PD with Applications to Periodontal Therapies. [PDF]

Pharmaceutics
Rakoczy R, Machoy-Rakoczy M, Gutowska I.
europepmc   +1 more source

Modeling biological memory network by an autonomous and adaptive multi-agent system [PDF]

Hui Wei, Chenyue Feng, Fushun Li
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Spatio-temporal forecasting of dengue in the Americas through hybrid mechanistic and data-driven models: Systematic review and meta-analysis. [PDF]

Infect Dis Model
Castellanos Garzón JA, Plaza Gálvez LF, Plaza Bastidas KF, Betancur Agudelo JE, Piedrahita AR.   +4 more
europepmc   +1 more source

Molecular Modeling for Biological Systems [PDF]

Chemical & Engineering News Archive, 1989
openaire   +1 more source

Stochastic Modelling for Systems Biology

, 2006
D. Wilkinson
semanticscholar   +1 more source