Results 31 to 40 of about 6,067,666 (328)

Modelling codependence in biological systems

open access: yesIET Systems Biology, 2007
A central aim of systems biology is to elucidate the complex dynamic structure of biological systems within which functioning and control occur. The success of this endeavour requires a dialogue between the two quite distinct disciplines of life science and systems theory, and so drives the need for graphical notations which facilitate this dialogue ...
J J, Mandel   +2 more
openaire   +2 more sources

Computational Modelling of the Interactions Between Polyoxometalates and Biological Systems

open access: yesFrontiers in Chemistry, 2022
Polyoxometalates (POMs) structures have raised considerable interest for the last years in their application to biological processes and medicine. Within this area, our mini-review shows that computational modelling is an emerging tool, which can play an
Adrià Gil   +3 more
doaj   +1 more source

The (mathematical) modelling process in biosciences

open access: yesFrontiers in Genetics, 2015
In this communication we introduce a general framework and discussion on the role of models and the modelling process within the scientific activity in the biosciences realm.
Nestor V. Torres   +3 more
doaj   +1 more source

Do Termitaria Indicate the Presence of Groundwater? A Case Study of Hydrogeophysical Investigation on a Land Parcel with Termite Activity

open access: yesInsects, 2020
Termite nests have long been suggested to be good indicators of groundwater but only a few studies are available to demonstrate the relationship between the two.
Jamilu Bala Ahmed   +3 more
doaj   +1 more source

Analysis of Practical Identifiability of a Viral Infection Model. [PDF]

open access: yesPLoS ONE, 2016
Mathematical modelling approaches have granted a significant contribution to life sciences and beyond to understand experimental results. However, incomplete and inadequate assessments in parameter estimation practices hamper the parameter reliability ...
Van Kinh Nguyen   +3 more
doaj   +1 more source

A semantics, energy-based approach to automate biomodel composition

open access: yesPLoS ONE, 2022
Hierarchical modelling is essential to achieving complex, large-scale models. However, not all modelling schemes support hierarchical composition, and correctly mapping points of connection between models requires comprehensive knowledge of each model’s ...
Niloofar Shahidi   +4 more
doaj   +3 more sources

Finite level models of biological systems [PDF]

open access: yesAnnals of Biomedical Engineering, 1973
This paper attempts to define the concept of finite level models within the context of systems theory and to indicate the applicability of this concept to biological systems. The rationale for finite level models is considered, and the concepts of quantization and the techniques for achieving it are described.
D S, Gann, G L, Cryer, J D, Schoeffler
openaire   +2 more sources

Relation of Adverse Childhood Experiences to Clinical and Patient‐Reported Outcomes for Adults With Sickle Cell Disease: A Registry Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell   +8 more
wiley   +1 more source

Bioprocess systems engineering: transferring traditional process engineering principles to industrial biotechnology

open access: yesComputational and Structural Biotechnology Journal, 2012
The complexity of the regulatory network and the interactions that occur in the intracellular environment of microorganisms highlight the importance in developing tractable mechanistic models of cellular functions and systematic approaches for modelling ...
Michalis Koutinas   +3 more
doaj   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

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