Results 41 to 50 of about 6,631,455 (355)

Model-guided design of ligand-regulated RNAi for programmable control of gene expression [PDF]

, 2008
Progress in constructing biological networks will rely on the development of more advanced components that can be predictably modified to yield optimal system performance.
Chase L Beisel, Christina D Smolke, Kevin G Hoff, Koch AL, Travis S Bayer   +4 more
core   +5 more sources

Kinetic Modeling of Biological Systems [PDF]

, 2009
The dynamics of how the constituent components of a natural system interact defines the spatio-temporal response of the system to stimuli. Modeling the kinetics of the processes that represent a biophysical system has long been pursued with the aim of improving our understanding of the studied system. Due to the unique properties of biological systems,
Haluk, Resat, Linda, Petzold, Michel F, Pettigrew   +2 more
openaire   +2 more sources

The (mathematical) modelling process in biosciences

Frontiers in Genetics, 2015
In this communication we introduce a general framework and discussion on the role of models and the modelling process within the scientific activity in the biosciences realm.
Nestor V. Torres, Nestor V. Torres, Guido eSantos, Guido eSantos   +3 more
doaj   +1 more source

Do Termitaria Indicate the Presence of Groundwater? A Case Study of Hydrogeophysical Investigation on a Land Parcel with Termite Activity

Insects, 2020
Termite nests have long been suggested to be good indicators of groundwater but only a few studies are available to demonstrate the relationship between the two.
Jamilu Bala Ahmed, Abdullahi Salisu, Biswajeet Pradhan, Abdullah M. Alamri   +3 more
doaj   +1 more source

Data-driven modelling of biological multi-scale processes

, 2015
Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales.
Hasenauer, Jan, Hross, Sabrina, Jagiella, Nick, Theis, Fabian J.   +3 more
core   +1 more source

A semantics, energy-based approach to automate biomodel composition

PLoS ONE, 2022
Hierarchical modelling is essential to achieving complex, large-scale models. However, not all modelling schemes support hierarchical composition, and correctly mapping points of connection between models requires comprehensive knowledge of each model’s ...
Niloofar Shahidi, Michael Pan, Kenneth Tran, Edmund J. Crampin, David P. Nickerson   +4 more
doaj   +3 more sources

Analysis of Practical Identifiability of a Viral Infection Model. [PDF]

PLoS ONE, 2016
Mathematical modelling approaches have granted a significant contribution to life sciences and beyond to understand experimental results. However, incomplete and inadequate assessments in parameter estimation practices hamper the parameter reliability ...
Van Kinh Nguyen, Frank Klawonn, Rafael Mikolajczyk, Esteban A Hernandez-Vargas   +3 more
doaj   +1 more source

Qualitative modelling and analysis of regulations in multi-cellular systems using Petri nets and topological collections [PDF]

, 2010
In this paper, we aim at modelling and analyzing the regulation processes in multi-cellular biological systems, in particular tissues. The modelling framework is based on interconnected logical regulatory networks a la Rene Thomas equipped with ...
A. B. Stundzia, A. Spicher, C. Chaouiya, C. Chaouiya, C. Chaouiya, C. Chaouiya, C.M. Vide, F. Pommereau, F. Pommereau, Francesco Bernardini, Franck Pommereau, Gabriel Ciobanu, H. Klaudel, H. Klaudel, Hanna Klaudel, J. Saez-Rodriguez, J.-L. Giavitto, J.-L. Giavitto, J.-L. Giavitto, J.-L. Giavitto, J.-L. Giavitto, J.-L. Giavitto, Jean-Louis Giavitto, K. Jensen, K. Takahashi, L. Sánchez, Maciej Koutny, O. Michel, P. Barbier Barbier de Reuille, R. Thomas, R. Thomas, R. Thomas, S. Castagnet   +32 more
core   +6 more sources

The fractional Keller-Segel model [PDF]

, 2006
The Keller-Segel model is a system of partial differential equations modelling chemotactic aggregation in cellular systems. This model has blowing up solutions for large enough initial conditions in dimensions d >= 2, but all the solutions are regular in
Brenner M P, Brenner M P, Carlos Escudero, Herrero M A, Herrero M A, Klafter J, Levandowsky M, Murray J D, Nagai T, Osaki K   +9 more
core   +1 more source

Rewriting systems and the modelling of biological systems [PDF]

Comparative and Functional Genomics, 2004
AbstractThis paper gives a brief survey of the use of algebraic rewriting systems for modelling and simulating various biological processes, particularly at the cellular level. Copyright © 2004 John Wiley & Sons, Ltd.
Giavitto, Jean-Louis, Malcolm, Grant, Michel, Olivier   +2 more
openaire   +2 more sources