Results 51 to 60 of about 6,631,455 (355)

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga   +56 more
wiley   +1 more source

Bioprocess systems engineering: transferring traditional process engineering principles to industrial biotechnology

open access: yesComputational and Structural Biotechnology Journal, 2012
The complexity of the regulatory network and the interactions that occur in the intracellular environment of microorganisms highlight the importance in developing tractable mechanistic models of cellular functions and systematic approaches for modelling ...
Michalis Koutinas   +3 more
doaj   +3 more sources

A Process Algebraical Approach to Modelling Compartmentalized Biological Systems [PDF]

open access: yes, 2007
This paper introduces Protein Calculus, a special modeling language designed for encoding and calculating the behaviors of compartmentilized biological systems.
Ihekwaba, Adaoha, Mardare, Radu
core   +1 more source

Narrative-based computational modelling of the Gp130/JAK/STAT signalling pathway. [PDF]

open access: yes, 2008
BACKGROUND: Appropriately formulated quantitative computational models can support researchers in understanding the dynamic behaviour of biological pathways and support hypothesis formulation and selection by "in silico" experimentation.
A Herrmann   +37 more
core   +7 more sources

Finite level models of biological systems [PDF]

open access: yesAnnals of Biomedical Engineering, 1973
This paper attempts to define the concept of finite level models within the context of systems theory and to indicate the applicability of this concept to biological systems. The rationale for finite level models is considered, and the concepts of quantization and the techniques for achieving it are described.
D S, Gann, G L, Cryer, J D, Schoeffler
openaire   +2 more sources

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez   +13 more
wiley   +1 more source

A Graphical Approach for Hybrid Simulation of 3D Diffusion Bio-Models via Coloured Hybrid Petri Nets

open access: yesModelling and Simulation in Engineering, 2020
Three-dimensional modelling of biological systems is imperative to study the behaviour of dynamic systems that require the analysis of how their components interact in space. However, there are only a few formal tools that offer a convenient modelling of
Amr Ismail   +3 more
doaj   +1 more source

The finding and researching algorithm for potentially oscillating enzymatic systems

open access: yesВавиловский журнал генетики и селекции, 2021
Many processes in living organisms are subject to periodic oscillations at different hierarchical levels of their organization: from molecular-genetic to population and ecological. Oscillatory processes are responsible for cell cycles in both prokaryotes
T. N. Lakhova   +3 more
doaj   +1 more source

Deterministic and stochastic P systems for modelling cellular processes [PDF]

open access: yes, 2010
This paper presents two approaches based on metabolic and stochastic P systems, together with their associated analysis methods, for modelling biological sys- tems and illustrates their use through two case studies.Kingdom's Engineering and Physical ...
A Castellini   +28 more
core   +1 more source

Modelling codependence in biological systems

open access: yesIET Systems Biology, 2007
A central aim of systems biology is to elucidate the complex dynamic structure of biological systems within which functioning and control occur. The success of this endeavour requires a dialogue between the two quite distinct disciplines of life science and systems theory, and so drives the need for graphical notations which facilitate this dialogue ...
J J, Mandel   +2 more
openaire   +2 more sources

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