Results 71 to 80 of about 44,204 (260)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Examination of Scanner Precision by Analysing Orthodontic Parameters
Balkan Journal of Dental Medicine, 2017 Background: 3D modelling in orthodontics is becoming an increasingly widespread technique in practice. One of the significant questions already being asked is related to determining the precision of the scanner used for generating surfaces on a 3D model ...
Majstorović Nemanja +6 more
doaj +1 more source
Statistical modelling of the service life prediction of painted surfaces
International Journal of Strategic Property Management, 2015 Service life prediction assumes a primary role as it allows a more rational use of construction elements. This constitutes a useful tool in the definition of preventive maintenance plans providing an increase in performance.
C. Chai +3 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Archeomatica, 2016 The Shape and Semantics Modelling Group of CNR-IMATI (an Institute of the Italian National Research Council) is active on several research topics related to shape modelling and retrieval.
Bianca Falcidieno
doaj +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A probabilistic approach for modelling deterioration of asphalt surfaces
Journal of the South African Institution of Civil Engineers, 2012 This paper details findings from the New Zealand Transport Agency's research project by Henning and Roux (2008). It forms part of the overall New Zealand Long-term Pavement Performance (LTPP) programme.
T F P Henning, D C Roux
doaj
Biomechanics of the natural, arthritic, and replaced human ankle joint
Journal of Foot and Ankle Research, 2014 The human ankle joint complex plays a fundamental role in gait and other activities of daily living. At the same time, it is a very complicated anatomical system but the large literature of experimental and modelling studies has not fully described the ...
Alberto Leardini +2 more
doaj +1 more source
Modelling finite geometries on surfaces
Discrete Mathematics, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source