Results 221 to 230 of about 2,719,550 (270)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

OrbiTox: a visualization platform for NAMs and read-across exploration of multi-domain data. [PDF]

Front Pharmacol
Ross A, Gombar V, Sedykh A, Green AJ, Borrel A, Kidd B, Phillips J, Shah M, Phadke D, Mav D, Balik-Meisner M, Howard B, Shah R, Kleinstreuer NC, Casey WM.   +14 more
europepmc   +1 more source

AgentMol: Multi-Model AI System for Automatic Drug-Target Identification and Molecule Development. [PDF]

Methods Protoc
Karabowicz P, Charkiewicz R, Charkiewicz A, Sulewska A, Nikliński J.   +4 more
europepmc   +1 more source

Artificial Intelligence Empowered New Materials: Discovery, Synthesis, Prediction to Validation. [PDF]

Nanomicro Lett
Cao Y, Fu H, Lu J, Chen Y, Jing T, Fan X, Xu B.   +6 more
europepmc   +1 more source

Integrating Artificial Intelligence into Circular Strategies for Plastic Recycling and Upcycling. [PDF]

Polymers (Basel)
Valle-Bravo AV, González CL, González-Soto RA, Serrano LAG, García JAC, Flores-Huicochea E.   +5 more
europepmc   +1 more source

Graph Neural Networks vs. Traditional QSAR: A Comprehensive Comparison for Multi-Label Molecular Odor Prediction. [PDF]

Molecules
Wen T, Cai X, Li J.
europepmc   +1 more source

High-Throughput Toxicity Screening with <i>C. elegans</i>: Current Platforms, Key Advantages, and Future Directions. [PDF]

Environ Sci Technol
Crombie TA, Pamminger T, Andersen EC, Glaberman S.   +3 more
europepmc   +1 more source

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