Results 251 to 260 of about 3,531,989 (315)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Protecting your skin: a highly accurate LSTM network integrating conjoint features for predicting chemical-induced skin irritation. [PDF]

J Cheminform
Duy HA, Srisongkram T.
europepmc   +1 more source

A Statistical Exploration of QSAR Models in Cancer Risk Assessment: A Case Study on Pesticide-Active Substances and Metabolites. [PDF]

Toxics
Greco S, Bossa C, Battistelli CL, Giuliani A.   +3 more
europepmc   +1 more source

A workflow for modeling radiolysis in chemically, physically, and geometrically complex scenarios. [PDF]

iScience
De Salvo G, Merkens S, Körner A, Fritsch B, Malgaretti P, Hutzler A, Chuvilin A.   +6 more
europepmc   +1 more source

Carbohydrate Synthesis is Entering the Data-Driven Digital Era. [PDF]

Chemistry
Sletten ET, Wolf JB, Danglad-Flores J, Seeberger PH.   +3 more
europepmc   +1 more source

Fate-tox: fragment attention transformer for E(3)-equivariant multi-organ toxicity prediction. [PDF]

J Cheminform
Ha S, Bang D, Kim S.
europepmc   +1 more source

VirNucPro: an identifier for the identification of viral short sequences using six-frame translation and large language models. [PDF]

Brief Bioinform
Li J, Mi J, Lin W, Tian F, Wan J, Gao J, Tong Y.   +6 more
europepmc   +1 more source

Chemical Models for the Chemical Nature of Endogenous Digitalis [PDF]

Journal of Enzyme Inhibition, 1991
The inability or the capacity to promote the phosphorylation of Na+/K(+)-transporting ATPase (Na/K-ATPase) from [32P]Pi is shown to differentiate between mechanistically digitalis-unlike and digitalis-like inhibitors of this enzyme known to be the receptor for all digitalis actions. A negative or positive response in the phosphorylation promotion assay
Karl-Heinz Menke, Kurt R. H. Repke, Jürgen Weiland   +2 more
openaire   +2 more sources

Sensitivity Analysis for Chemical Models [PDF]

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Francesca Campolongo, Marco Ratto, Stefano Tarantola, Andrea Saltelli   +3 more
openaire   +3 more sources

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Tutorial: The modelling of chemical processes

Analytica Chimica Acta, 2009
The modelling of chemical processes entails the computation of the concentration profiles of all reaction species as a function of the reaction time. The basis for the calculations is the system of differential equations (ODE's) that is defined by the reaction mechanism.
McCann, Nichola, Maeder, Marcel
openaire   +3 more sources