Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Creation of 3D Multi-Body Orthodontic Models by Using Independent Imaging Sensors
In the field of dental health care, plaster models combined with 2D radiographs are widely used in clinical practice for orthodontic diagnoses. However, complex malocclusions can be better analyzed by exploiting 3D digital dental models, which allow ...
Armando Viviano Razionale +2 more
doaj +1 more source
In vitro, ex vivo, and in vivo models for dental pulp regeneration
Based on the concept of tissue engineering (Cells—Scaffold—Bioactive molecules), regenerative endodontics appeared as a new notion for dental endodontic treatment.
Sofia Silvia Piglionico +5 more
doaj +1 more source
Innovations that Address Socioeconomic, Cultural, and Geographic Barriers to Preventive Oral Health Care [PDF]
This report focuses on nine oral health innovations that integrate service delivery and workforce models in order to reduce or eliminate socioeconomic, geographic, and cultural barriers to care.
D. Krol +4 more
core
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Therapeutic effects of dental pulp stem cells on vascular dementia in rat models
Dental pulp stem cells are a type of adult stem cells with strong proliferative ability and multi-differentiation potential. There are no studies on treatment of vascular dementia with dental pulp stem cells.
Xue-Mei Zhang +11 more
doaj +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Laser Densification of Extruded Dental Porcelain Bodies in Multi-Material Laser Densification (MMLD) Process [PDF]
In this study commercial dental porcelain powder was deposited via slurry extrusion and laser densified to fabricate dental restorations in a Multi-Material Laser Densification (MMLD) process. The processing conditions for laser densification of single
Cameron, Thomas B. +3 more
core +1 more source
[Photoelastic models applied to dental restorations].
Objetivo: Mejorar la comprensión de los cambios generados por los procedimientos restaurativos a través de modelos fotoelásticos. La reconstrucción dental debe fundamentarse en principios de oclusión para no provocar puntos prematuros de contacto durante los procedimientso de preparación y restauración que pueden provocar transtornos como el ...
Marín-Miranda, Miriam +2 more
openaire +2 more sources
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source

